Effect of transversus abdominis plane block in combination with general anesthesia on perioperative opioid consumption, hemodynamics, and recovery in living liver donors: The prospective, double-blinded, randomized study

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dc.authoridOZGUL, Ulku/0000-0003-3738-1751
dc.authoridcolak, yusuf ziya/0000-0002-8729-8705
dc.authoridToprak, Hüseyin İlksen/0000-0001-9293-8116
dc.authoridUçar, Muharrem/0000-0002-1232-9829
dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridErdogan, Mehmet Ali/0000-0002-3860-6919
dc.authorwosidErdogan, Mehmet Ali/ABI-7224-2020
dc.authorwosidOZGUL, Ulku/ABI-6823-2020
dc.authorwosidcolak, yusuf ziya/ABH-3032-2020
dc.authorwosidToprak, Hüseyin İlksen/AAN-4023-2020
dc.authorwosidUçar, Muharrem/ABH-7761-2020
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.contributor.authorErdogan, Mehmet A.
dc.contributor.authorOzgul, Ulku
dc.contributor.authorUcar, Muharrem
dc.contributor.authorYalin, Mehmet R.
dc.contributor.authorColak, Yusuf Z.
dc.contributor.authorColak, Cemil
dc.contributor.authorToprak, Huseyin I.
dc.date.accessioned2024-08-04T20:43:01Z
dc.date.available2024-08-04T20:43:01Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackgroundTransversus abdominis plane (TAP) block provides effective postoperative analgesia after abdominal surgeries. It can be also a useful strategy to reduce perioperative opioid consumption, support intraoperative hemodynamic stability, and promote early recovery from anesthesia. The aim of this prospective randomized double-blind study was to assess the effect of subcostal TAP blocks on perioperative opioid consumption, hemodynamic, and recovery time in living liver donors. MethodsThe prospective, double-blinded, randomized controlled study was conducted with 49 living liver donors, aged 18-65years, who were scheduled to undergo right hepatectomy. Patients who received subcostal TAP block in combination with general anesthesia were allocated into Group 1, and patients who received general anesthesia alone were allocated into Group 2. The TAP blocks were performed bilaterally by obtaining an image with real-time ultrasound guidance using 0.5% bupivacaine diluted with saline to reach a total volume of 40mL. The primary outcome measure in our study was perioperative remifentanil consumption. Secondary outcomes were mean blood pressure (MBP), heart rate (HR), mean desflurane requirement, anesthesia recovery time, frequency of emergency vasopressor use, total morphine use, and length of hospital stay. ResultsTotal remifentanil consumption and the anesthesia recovery time were significantly lower in Group 1 compared with Group 2. Postoperative total morphine use and length of hospital stay were also reduced. Changes in the MAP and HR were similar in the both groups. There were no significant differences in HR and MBP between groups at any time. ConclusionsCombining subcostal TAP blocks with general anesthesia significantly reduced perioperative and postoperative opioid consumption, provided shorter anesthesia recovery time, and length of hospital stay in living liver donors.en_US
dc.identifier.doi10.1111/ctr.12931
dc.identifier.issn0902-0063
dc.identifier.issn1399-0012
dc.identifier.issue4en_US
dc.identifier.pmid28199752en_US
dc.identifier.scopus2-s2.0-85015201040en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1111/ctr.12931
dc.identifier.urihttps://hdl.handle.net/11616/97729
dc.identifier.volume31en_US
dc.identifier.wosWOS:000398589100019en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectanesthesiaen_US
dc.subjectliving liver donoren_US
dc.subjectrecoveryen_US
dc.subjectremifentanilen_US
dc.subjecttransversus abdominis plane blocken_US
dc.titleEffect of transversus abdominis plane block in combination with general anesthesia on perioperative opioid consumption, hemodynamics, and recovery in living liver donors: The prospective, double-blinded, randomized studyen_US
dc.typeArticleen_US

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