Venous thromboemboli and exacerbations of COPD

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dc.authoridGunen, Hakan/0000-0001-6631-4457
dc.authoridHacievliyagil, Suleyman Savas/0000-0002-2572-1870
dc.authoridGulbas, Gazi/0000-0002-9435-8307
dc.authorwosidGunen, Hakan/HKV-9202-2023
dc.authorwosidHacievliyagil, Suleyman Savas/ABI-7307-2020
dc.authorwosidGulbas, Gazi/ABI-5182-2020
dc.contributor.authorGunen, H.
dc.contributor.authorGulbas, G.
dc.contributor.authorIn, E.
dc.contributor.authorYetkin, O.
dc.contributor.authorHacievliyagil, S. S.
dc.date.accessioned2024-08-04T20:32:25Z
dc.date.available2024-08-04T20:32:25Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of the present study was to determine the prevalence of and risk factors for venous thromboembolism (VTE) in exacerbations of chronic obstructive pulmonary disease (COPD). COPD patients hospitalised with an exacerbation were included consecutively. Symptoms, signs and clinical, haematological and epidemiological parameters on admission were noted. All patients underwent computed tomographic angiography and ultrasonographic examination for deep vein thrombosis and pulmonary embolism (PE). Wells and Geneva scores were calculated. Patients were followed-up for 1 yr in order to determine mortality. Deep vein thrombosis and PE were detected in 14 and 18 patients, respectively. The prevalence of VTE was three times higher in patients with an exacerbation of unknown origin than in patients with an exacerbation of known origin (p=0.016). Of patients with VTE, 20 (95%) had high D-dimer levels. The negative predictive value of D-dimer testing was 0.98. Although the moderate-and high-risk categories of both the Wells and Geneva methods covered all PE patients, the Wells method identified 49% less potential patients for PE investigation. Mortality at 1 yr was higher (61.9% versus 31.8%) in VTE patients (p=0.013). VTE is a common problem in COPD patients hospitalised with an exacerbation, leading to high long-term mortality. D-dimer levels and the Wells criteria can be used to determine whether or not these patients are assessed for a thromboembolic event.en_US
dc.identifier.doi10.1183/09031936.00120909
dc.identifier.endpage1248en_US
dc.identifier.issn0903-1936
dc.identifier.issue6en_US
dc.identifier.pmid19926740en_US
dc.identifier.scopus2-s2.0-77953528445en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1243en_US
dc.identifier.urihttps://doi.org/10.1183/09031936.00120909
dc.identifier.urihttps://hdl.handle.net/11616/95060
dc.identifier.volume35en_US
dc.identifier.wosWOS:000278194000010en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEuropean Respiratory Soc Journals Ltden_US
dc.relation.ispartofEuropean Respiratory Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic obstructive pulmonary diseaseen_US
dc.subjectdeep vein thrombosisen_US
dc.subjectexacerbationen_US
dc.subjectmortalityen_US
dc.subjectpulmonary embolien_US
dc.titleVenous thromboemboli and exacerbations of COPDen_US
dc.typeArticleen_US

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