Biodegradable non-aromatic adhesive polyurethanes based on disaccharides for medical applications
dc.authorid | BALCIOGLU, Sevgi/0000-0003-0724-4772 | |
dc.authorid | BALCIOGLU, Sevgi/0000-0003-0724-4772 | |
dc.authorid | Ateş, Burhan/0000-0001-6080-229X | |
dc.authorid | Koytepe, Suleyman/0000-0002-4788-278X | |
dc.authorid | KARAASLAN, MERVE GOKSIN/0000-0003-2645-808X | |
dc.authorwosid | Köytepe, Süleyman/AAA-4168-2021 | |
dc.authorwosid | BALCIOGLU, Sevgi/O-3576-2015 | |
dc.authorwosid | BALCIOGLU, Sevgi/W-5874-2018 | |
dc.authorwosid | Ateş, Burhan/AAA-3730-2021 | |
dc.contributor.author | Ates, Burhan | |
dc.contributor.author | Koytepe, Suleyman | |
dc.contributor.author | Karaaslan, Merve Goksin | |
dc.contributor.author | Balcioglu, Sevgi | |
dc.contributor.author | Gulgen, Selam | |
dc.date.accessioned | 2024-08-04T20:38:01Z | |
dc.date.available | 2024-08-04T20:38:01Z | |
dc.date.issued | 2014 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | This work addresses synthesis, characterization, adhesive properties, protein adsorption and in vitro biodegradation of non-aromatic polyurethanes (NPUs). The following reactants were used in the syntheses of polyurethanes (PUs): non-aromatic 4,4'-Methylenebis(cyclohexyl isocyanate) (MCI), disaccharides (maltose and sucrose) and polyethylene glycol 200 (PEG 200). The NPUs exhibited low glass transition temperature (T-g) and good thermal stability. The dynamic contact angles on NPUs were influenced by the ratios of PEG 200-disaccharide monomer and the hard segment of the NPUs. The highest adhesion strength in whole polyurethanes was found as 307.6 +/- 50.1 kPa for 15% sucrose containing polyurethane. Protein adsorptions of polyurethane films were measured as average 10 pg Bovine Serum Albumin (BSA)/cm(2) and 5 mu g fibrinogen/cm(2) for maltose, and 15 mu g BSA/cm(2) and 5 mu g fibrinogen/cm(2) for sucrose. Biodegradability ratios of NPUs were in the range of 15-35% for 8 weeks depending on the disaccharides containing NPUs. (C) 2013 Elsevier Ltd. All rights reserved. | en_US |
dc.description.sponsorship | Scientific and Technical Research Council of Turkey (TUBITAK) [TBAG-(111T104)] | en_US |
dc.description.sponsorship | This study was supported by a grant (TBAG-(111T104)) to B. Ates from The Scientific and Technical Research Council of Turkey (TUBITAK). | en_US |
dc.identifier.doi | 10.1016/j.ijadhadh.2013.12.012 | |
dc.identifier.endpage | 96 | en_US |
dc.identifier.issn | 0143-7496 | |
dc.identifier.issn | 1879-0127 | |
dc.identifier.scopus | 2-s2.0-84891686597 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 90 | en_US |
dc.identifier.uri | https://doi.org/10.1016/j.ijadhadh.2013.12.012 | |
dc.identifier.uri | https://hdl.handle.net/11616/96314 | |
dc.identifier.volume | 49 | en_US |
dc.identifier.wos | WOS:000332141700013 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Sci Ltd | en_US |
dc.relation.ispartof | International Journal of Adhesion and Adhesives | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Polyurethane | en_US |
dc.subject | Novel adhesives | en_US |
dc.subject | Bioadhesive | en_US |
dc.title | Biodegradable non-aromatic adhesive polyurethanes based on disaccharides for medical applications | en_US |
dc.type | Article | en_US |