The influence of cigarette smoke on the epithelium of the vestibule: An electron microscopic study

Küçük Resim Yok

Tarih

2003

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Yonsei University College of Medicine

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

It is known that cigarette smoke induces cytological alterations on the respiratory and olfactory mucosa of the nasal cavity. We evaluated whether cigarette smoking had adverse effects on the epithelium of the vestibule, in the absence of any published ultrasutructural studies. We evaluated ten patients suffering from septum deviation, eight of whom were long-term smokers. While each layer of the epithelium obtained from the non-smokers consisted of a homogeneous cell population, each from the long-term smokers consisted of a heterogeneous cell population. The most prominent changes occurred in the shape and size of the cells and nuclei, the number and length of the cytoplasmic projections, the number and distribution pattern of the desmosomes, and the width of the intercellular spaces. We concluded that cigarette smoke produces hyperplastic and dysplastic changes, important factors related with cancer development, on the epithelium of the vestibule.

Açıklama

Anahtar Kelimeler

Cigarette smoke, Electron microscopy, Vestibule

Kaynak

Yonsei Medical Journal

WoS Q Değeri

Scopus Q Değeri

Q2

Cilt

44

Sayı

4

Künye