Gastrointestinal amyloidosis occurring in three different patterns: Case series

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Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

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Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Abstract: Systemic amyloidosis is a rare disease characterized by extracellular accumulation of amyloid protein in one or more organs. In patients with systemic amyloidosis, the most frequently affected organs are kidney and heart, followed by the nervous system, soft tissues, and lungs. Small bowel and liver involvement are also frequent in systemic amyloidosis. Gastrointestinal (GI) findings are common, and the degree of organ involvement determines the symptoms. Patients usually have nonspecific findings such as abdominal pain, nausea, diarrhea, and dysphagia, which may delay the appropriate diagnosis. Liver involvement occurs in the majority of patients, but the symptoms typically do not happen unless a marked hepatic amyloid deposition occurs. Diagnosis is by tissue biopsy. Treatment and prognosis depend on the underlying disease. GI system involvement is a sign of poor prognosis. In this case series, five patients who were diagnosed with gastrointestinal system amyloidosis in our clinic are presented.

Açıklama

Anahtar Kelimeler

Kaynak

Annals of Medical Research

WoS Q Değeri

Scopus Q Değeri

Cilt

26

Sayı

5

Künye

ÇALIŞKAN A. R,ÇAĞIN Y. F,BİLGİÇ Y,YILDIRIM O,ERDOĞAN M. A,SEÇKİN Y,ALAN S,SOYLU N. K (2019). Gastrointestinal amyloidosis occurring in three different patterns: Case series. Annals of Medical Research, 26(5), 955 - 958. Doi: 10.5455/annalsmedres.2019.02.082