Renal Behcet's Disease: An Update

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dc.authoridAkar, Harun/0000-0002-0936-8691
dc.authoridtaskapan, hulya/0000-0001-8736-4779
dc.authoridAdibelli, Zelal/0000-0001-7091-5204
dc.authoridToprak, Omer/0000-0002-2865-1687
dc.authoridAksu, Kenan/0000-0001-8889-2688
dc.authoridARICI, MUSTAFA/0000-0002-4055-7896
dc.authorwosidDiri, Banu/AAA-1020-2021
dc.authorwosidAkpolat, Tekin/IAM-7772-2023
dc.authorwosidAkar, Harun/X-9223-2019
dc.authorwosidtaskapan, hulya/ABI-7737-2020
dc.authorwosidAdibelli, Zelal/B-1781-2019
dc.authorwosidToprak, Omer/ABA-5812-2020
dc.authorwosidAksu, Kenan/HLH-8218-2023
dc.contributor.authorAkpolat, Tekin
dc.contributor.authorDilek, Melda
dc.contributor.authorAksu, Kenan
dc.contributor.authorKeser, Goekhan
dc.contributor.authorToprak, Oemer
dc.contributor.authorCirit, Mustafa
dc.contributor.authorOguz, Yusuf
dc.date.accessioned2024-08-04T20:31:05Z
dc.date.available2024-08-04T20:31:05Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aims of this study are (1) to report 33 patients with Behcet's disease (BD) having various renal manifestations, and (2) to update Current data using our patients and published papers about BD and renal manifestations. Methods: The PubMed database was searched using the terms BD or Behcet's syndrome. We found reports of 94 patients (including ours) with BD and specific renal diseases (amyloidosis, 39; glomerulonephritis [GN], 37; renal vascular disease, 19; interstitial nephritis, 1). Results: The presentation of renal disease was edema/nephrotic syndrome in 12 patients (36%). Renal disease was incidentally diagnosed by routine Urine analysis and measurement Of Serum creatinine level in 20 patients (61 %). Renal failure was present in 23 patients (70%) and 5 of them have had cyclosporine treatment. The frequency of renal disease among BD patients has been reported to vary from less than 1 to 29%. Conclusions: The clinical spectrum OF renal BD shows a wide variation. Amyloidosis (AA type), GN, and macroscopic/microscopic vascular disease are the main causes of renal BD. Patients with vascular involvement have a high risk of amyloidosis and amyloidosis is the most common cause of renal failure in BD. Several types of glomerular lesions are seen in BD. Current treatment options for renal BD are not evidence based. Radiological vascular intervention combined with immunosuppressive drugs can be useful in selected cases. Routine Urine analysis and measurement of serum creatinine level are needed Cor early diagnosis of renal BD. (C) 2008 Elsevier Inc. All rights reserved. Semin Arthritis Rheum 38:241-248en_US
dc.identifier.doi10.1016/j.semarthrit.2007.11.001
dc.identifier.endpage248en_US
dc.identifier.issn0049-0172
dc.identifier.issn1532-866X
dc.identifier.issue3en_US
dc.identifier.pmid18221990en_US
dc.identifier.scopus2-s2.0-56349142092en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage241en_US
dc.identifier.urihttps://doi.org/10.1016/j.semarthrit.2007.11.001
dc.identifier.urihttps://hdl.handle.net/11616/94699
dc.identifier.volume38en_US
dc.identifier.wosWOS:000261622100007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofSeminars in Arthritis and Rheumatismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet's diseaseen_US
dc.subjectamyloidosisen_US
dc.subjectglomerulonephritisen_US
dc.subjectrenal vascular diseaseen_US
dc.subjectinterstitial nephritisen_US
dc.subjectcyclosporineen_US
dc.subjecturemiaen_US
dc.titleRenal Behcet's Disease: An Updateen_US
dc.typeReview Articleen_US

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