Clinicopathologic Characteristics and Therapeutic Outcomes of Primary Gastrointestinal Non-Hodgkin's Lymphomas: 10 Years of Experience from a Single Center in Eastern Anatolia

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dc.authoridKAYA, Emin/0000-0001-8605-8497
dc.authoridErkurt, Mehmet Ali/0000-0002-3285-417X
dc.authorwosidBasaran, Yalcin/D-7227-2017
dc.authorwosidKAYA, Emin/W-2951-2017
dc.authorwosidErkurt, Mehmet Ali/ABI-7232-2020
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorAydogdu, Ismet
dc.contributor.authorKuku, Irfan
dc.contributor.authorKaya, Emin
dc.contributor.authorBasaran, Yalcin
dc.date.accessioned2024-08-04T20:31:16Z
dc.date.available2024-08-04T20:31:16Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The objective of this retrospective study was to report the clinicopathological data and the treatment outcomes in patients with primary gastrointestinal non-Hodgkin's lymphoma. Patients and Methods: We carried out a retrospective analysis of 41 patients (22 females, 18 males, median age 58 and range 18-90 years) who presented to our department with histopathological diagnosis of primary gastrointestinal non-Hodgkin's lymphoma between 1995 and 2004. Results: The stomach was the most common extranodal site and was seen in 25 of 41 (61%) patients. At presentation 28 (68.3%) patients had gastrointestinal symptoms while 27 (65.9%) had B symptoms. The range of follow-up was 2-84 months with a median of 9 months. The overall survival rate was 3 years for 25 (61.2%) patients. The 3-year overall survival rate was better in patients with early-stage disease (stages I and II1) who were treated with surgery plus chemotherapy and/or radiation therapy than in those treated with chemotherapy alone (91.6 vs. 50%, p < 0.05). The disease had a significant impact on both the progression-free survival and overall survival rates. Conclusion: Our data showed that surgical resection prior to postoperative chemotherapy was a better option for patients with early-stage disease with better patient survival. Copyright (C) 2009 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000226295
dc.identifier.endpage406en_US
dc.identifier.issn1011-7571
dc.identifier.issn1423-0151
dc.identifier.issue5en_US
dc.identifier.pmid19648764en_US
dc.identifier.scopus2-s2.0-68249153474en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage399en_US
dc.identifier.urihttps://doi.org/10.1159/000226295
dc.identifier.urihttps://hdl.handle.net/11616/94848
dc.identifier.volume18en_US
dc.identifier.wosWOS:000268678200011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGastrointestinal non-Hodgkin's lymphomaen_US
dc.subjectPrognostic factorsen_US
dc.subjectClinicopathologic featuresen_US
dc.subjectSurvivalen_US
dc.titleClinicopathologic Characteristics and Therapeutic Outcomes of Primary Gastrointestinal Non-Hodgkin's Lymphomas: 10 Years of Experience from a Single Center in Eastern Anatoliaen_US
dc.typeArticleen_US

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