Treatment of systemic sclerosis-associated digital ulcers: recommendations of the Turkish Society for Rheumatology

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dc.authoridKaradag, Duygu Temiz/0000-0002-5891-2032
dc.authoridTUFAN, ABDURRAHMAN/0000-0001-6244-9362
dc.authoridAvanoglu Guler, Aslihan/0000-0001-9866-9797
dc.authoridErdogan, Mustafa/0000-0003-4087-6667
dc.authoridkucuksahin, orhan/0000-0003-4530-2304
dc.authorwosidKaradag, Duygu Temiz/G-3489-2018
dc.authorwosidTUFAN, ABDURRAHMAN/A-7613-2016
dc.authorwosidAvanoglu Guler, Aslihan/JHU-7832-2023
dc.authorwosidErdogan, Mustafa/AAF-6915-2019
dc.authorwosidkucuksahin, orhan/GZA-3287-2022
dc.contributor.authorKaradag, D. Temiz
dc.contributor.authorYalcinkaya, Y.
dc.contributor.authorAkdogan, A.
dc.contributor.authorAvanoglu, A.
dc.contributor.authorBes, C.
dc.contributor.authorBirlik, A. M.
dc.contributor.authorCefle, A.
dc.date.accessioned2024-08-04T20:54:34Z
dc.date.available2024-08-04T20:54:34Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective Digital ulcers (DUs) are associated with a significant burden in systemic sclerosis (SSc) by leading to severe pain, physical disability, and reduced quality of life. This effort aimed to develop recommendations of the Turkish Society for Rheumatology (TRD) on the management of DUs associated with SSc. Methods In the first meeting held in December 2020 with the participation of a task force consisting of 23 rheumatologists the scope of the recommendations and research questions were determined. A systematic literature review was conducted by 5 fellows and results were presented to the task force during the second meeting. The Oxford system was used to determine the level of evidence. The preliminary recommendations were discussed, modified, and voted by the task force and then by members of TRD via e-mail invitation allowing personalised access to a web-based questionnaire [SurveyMonkey((R))]. Results A total of 23 recommendations under 7 main headings were formulated covering non-pharmacological measures for the prevention of DUs and pharmacological treatments including vasodilators, anti-aggregants, antibiotics, wound care, pain control, and interventions including sympathectomy, botulinum toxin, and surgery. Risk factors, poor prognostic factors, prevention of DU and adverse effects of medical treatments were reported as 4 overarching principles. Conclusion These evidence-based recommendations for the management of SSc-associated DUs were developed to provide a useful guide to all physicians who are involved in the care of patients with SSc, as well as to point out unmet needs in this field.en_US
dc.description.sponsorshipAbdi Ibrahim Pharmaceuticals Companyen_US
dc.description.sponsorship& nbsp;& nbsp;this study was supported by an unrestricted grant by Abdi Ibrahim Pharmaceuticals Company.en_US
dc.identifier.endpage1687en_US
dc.identifier.issn0392-856X
dc.identifier.issn1593-098X
dc.identifier.issue8en_US
dc.identifier.pmid37470234en_US
dc.identifier.scopus2-s2.0-85166442153en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1679en_US
dc.identifier.urihttps://hdl.handle.net/11616/101494
dc.identifier.volume41en_US
dc.identifier.wosWOS:001047737300015en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherClinical & Exper Rheumatologyen_US
dc.relation.ispartofClinical and Experimental Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectsystemic sclerosisen_US
dc.subjectdigital ulceren_US
dc.subjecttreatmenten_US
dc.subjectrecommendationen_US
dc.titleTreatment of systemic sclerosis-associated digital ulcers: recommendations of the Turkish Society for Rheumatologyen_US
dc.typeArticleen_US

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