Systemic Immune-Inflammation Index as a Predictor of Microvascular Dysfunction in Patients With Cardiac Syndrome X

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dc.authoridYaşar, Erdoğan/0000-0001-5882-3534
dc.authorwosidYaşar, Erdoğan/GOH-1219-2022
dc.contributor.authorYasar, Erdogan
dc.contributor.authorBayramoglu, Adil
dc.date.accessioned2024-08-04T20:51:55Z
dc.date.available2024-08-04T20:51:55Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe systemic immune inflammation index (SII; platelet count x neutrophil-lymphocyte ratio), a new marker, predicts adverse clinical outcomes in many conditions, including acute and chronic coronary syndromes, pulmonary embolism, cancers, and contrast nephropathy. The aim of this study was to determine the relationship between SII and microvascular dysfunction in patients with Cardiac Syndrome X (CSX); 105 patients with CSX and 105 patients with normal coronary arteries were included. Microvascular dysfunction was determined angiographically using myocardial blush grade (MBG) and total myocardial blush score (TMBS). We observed that the SII levels were higher in the CSX (+) group (687 [355-2211] vs 418 [198-1614], P<.001). The SII levels were also found to be significant independent predictors for CSX in multiple regression analysis (P=.001). SII levels >440 had 83.8% sensitivity and 55.2% specificity (area under the curve [AUC]: .923, 95% CI: .895-.999, P<.001) for predicting CSX. There is a significant correlation between SII levels and CSX.en_US
dc.identifier.doi10.1177/00033197221087777
dc.identifier.endpage621en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue7en_US
dc.identifier.pmid35403436en_US
dc.identifier.scopus2-s2.0-85129265057en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage615en_US
dc.identifier.urihttps://doi.org/10.1177/00033197221087777
dc.identifier.urihttps://hdl.handle.net/11616/100626
dc.identifier.volume73en_US
dc.identifier.wosWOS:000781824900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcardiac syndrome Xen_US
dc.subjectsystemic immune inflammation index (SII)en_US
dc.subjectmicrovascular dysfunctionen_US
dc.titleSystemic Immune-Inflammation Index as a Predictor of Microvascular Dysfunction in Patients With Cardiac Syndrome Xen_US
dc.typeArticleen_US

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