Effects of intraoperative different fluid therapy protocols on postoperative renal functions

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dc.contributor.authorOzcan, Ayca Tuba Dumanli
dc.contributor.authorTas, Nisan
dc.contributor.authorErsoy, Umut Cahit
dc.contributor.authorYamen, Kevser
dc.contributor.authorYilmaz, Yusuf
dc.contributor.authorOzcan, Erdal
dc.contributor.authorCeylan, Cengiz
dc.date.accessioned2026-04-04T13:33:13Z
dc.date.available2026-04-04T13:33:13Z
dc.date.issued2024
dc.departmentİnönü Üniversitesi
dc.description.abstractPurpose Planning intraoperative fluid therapy in patients undergoing major abdominal surgery is important. It was aimed to define the difference between fluid therapy protocols for renal function, bleeding and postoperative service follow-ups. Materials and methods This is an observational case-controlled prospective study. Sixty patients aged 18-65 years who had undergone pancreatic surgery between December 2023- February 2023 were included in the study. Liberal (Group 1; n = 30) and targeted fluid therapies (Group 2; n = 30) were administered to the patients. Liberal fluid therapy was planned with 8-10 ml/kg/h crystalloid infusion. The targeted fluid therapy (TFT) group (Group 2; n = 30) began with a 2 ml/kg/h crystalloid infusion at the baseline. Additional fluid boluses were given in 250 ml of colloid infused over 10 min if PVI was > 13% for at least five minutes. The patients were staged using the KDIGO (Kidney Disease: Improving Global Outcomes) criteria. The amount of bleeding during surgery was recorded for both groups. Results No significant difference was observed in postoperative renal function. A significant difference was observed in the amount of intraoperative bleeding. The amount of bleeding was greater in patients managed with liberal fluid therapy. No significant difference was observed between the groups in the oral intake (hour), drain withdrawal (hour) mobilization (hour) and discharge (day) times and there isn't any statistically significant differance between groups in cost effectivity (p>0.05). Conclusion Kidney function was preserved during individualized targeted fluid therapy using non-invasive haemodynamic monitoring parameters.
dc.identifier.doi10.1186/s12871-024-02679-3
dc.identifier.issn1471-2253
dc.identifier.issue1
dc.identifier.orcid0000-0002-9881-8534
dc.identifier.orcid0000-0002-5878-8027
dc.identifier.orcid0000-0001-8642-6464
dc.identifier.pmid39210300
dc.identifier.scopus2-s2.0-85202727131
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1186/s12871-024-02679-3
dc.identifier.urihttps://hdl.handle.net/11616/108987
dc.identifier.volume24
dc.identifier.wosWOS:001303640700001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBmc
dc.relation.ispartofBmc Anesthesiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250329
dc.subjectPancreatic surgery
dc.subjectTargeted fluid therapy
dc.subjectKDIGO criteria
dc.titleEffects of intraoperative different fluid therapy protocols on postoperative renal functions
dc.typeArticle

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