Coexistence of restless legs syndrome and multiple sclerosis aggravates anxiety and depression

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dc.authoridTERZİ, Murat/0000-0002-3586-9115
dc.authoridSiva, Aksel/0000-0002-8340-6641
dc.authoridUygunoglu, Ugur/0000-0003-2866-4004
dc.authoridşen, sedat/0000-0001-8048-6845
dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authoridGündüz, Tuncay/0000-0003-4241-0908
dc.authoridDemirkiran, Meltem/0000-0002-4649-5315
dc.authorwosidBOZ, Cavit/V-5127-2017
dc.authorwosidKurtuncu, Murat/L-2705-2015
dc.authorwosidTERZİ, Murat/AAA-1284-2021
dc.authorwosidKarabudak, Rana/HJH-2490-2023
dc.authorwosidSiva, Aksel/A-5132-2016
dc.authorwosidUygunoglu, Ugur/S-9141-2016
dc.authorwosidşen, sedat/AAB-5529-2020
dc.contributor.authorSevim, Serhan
dc.contributor.authorDemirkiran, Meltem
dc.contributor.authorTerzi, Murat
dc.contributor.authorYuceyar, Nur
dc.contributor.authorTasdelen, Bahar
dc.contributor.authorIdiman, Egemen
dc.contributor.authorKurtuncu, Murat
dc.date.accessioned2024-08-04T20:51:54Z
dc.date.available2024-08-04T20:51:54Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Among the comorbidities that accompany multiple sclerosis (MS), restless legs syndrome (RLS) is one of the most common. Anxiety and depression are common psychological comorbidities that impact the quality of life of patients with MS (PwMS), as well as patients with RLS. Objective: To investigate the psychiatric burden of MS and RLS coexistence, we conducted a nationwide, multicenter and cross-sectional survey. Methods: Participants were assessed by using demographic and clinical parameters along with the Hamilton Anxiety and Hamilton Depression Scales (HAM-A and HAM-D). Results: Out of the 1,068 participants, 173 (16.2%) were found to have RLS [RLS(+)] and 895 (83.8%) did not [RLS(-)]. The mean scores for HAM-A and HAM-D were significantly higher among RLS(+) subjects than among RLS(-) subjects (p<0.001 for all variables). Conclusions: According to our data, the presence of RLS in PwMS may increase the occurrence of both anxiety and depression symptoms. Awareness and treatment of RLS in PwMS could possibly reduce the symptoms of psychiatric comorbidities originating from RLS.en_US
dc.identifier.doi10.1590/0004-282X-ANP-2020-0400
dc.identifier.endpage172en_US
dc.identifier.issn0004-282X
dc.identifier.issn1678-4227
dc.identifier.issue2en_US
dc.identifier.pmid35195221en_US
dc.identifier.scopus2-s2.0-85128159776en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage168en_US
dc.identifier.urihttps://doi.org/10.1590/0004-282X-ANP-2020-0400
dc.identifier.urihttps://hdl.handle.net/11616/100602
dc.identifier.volume80en_US
dc.identifier.wosWOS:000759804200001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Arquivos Neuro- Psiquiatriaen_US
dc.relation.ispartofArquivos De Neuro-Psiquiatriaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMultiple Sclerosisen_US
dc.subjectRestless Legs Syndromeen_US
dc.subjectDepressionen_US
dc.subjectAnxietyen_US
dc.subjectMental Disordersen_US
dc.titleCoexistence of restless legs syndrome and multiple sclerosis aggravates anxiety and depressionen_US
dc.typeArticleen_US

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