Effect of ovarian stimulation with recombinant follicle-stimulating hormone, gonadotropin-releasing hormone agonist and antagonists, on follicular fluid stem cell factor and serum urocortin 1 levels on the day of oocyte retrieval

dc.authoridCelik, ebru/0000-0002-0774-4294
dc.authoridTURKCUOGLU, ILGIN/0000-0002-8342-1956
dc.authorwosidUlas, mustafa/KIE-9518-2024
dc.authorwosidÖzerol, İbrahim Halil/ABI-8015-2020
dc.authorwosidCelik, ebru/X-4343-2019
dc.contributor.authorCelik, Onder
dc.contributor.authorCelik, Ebru
dc.contributor.authorYilmaz, Ercan
dc.contributor.authorCelik, Niluefer
dc.contributor.authorTurkcuoglu, Ilgin
dc.contributor.authorUlas, Mustafa
dc.contributor.authorKumbak, Banu
dc.date.accessioned2024-08-04T20:37:57Z
dc.date.available2024-08-04T20:37:57Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTo compare the serum and follicular fluid (FF) concentrations of stem cell factor (SCF) as well as the serum urocortin 1 (UCN1) concentration in gonadotropin-releasing hormone antagonist (GnRH-ant) and gonadotropin-releasing hormone agonist (GnRH-a) protocols for controlled ovarian hyperstimulation (COH) in IVF patients. Follicular fluids and blood samples of 42 infertile women undergoing COH for IVF-embryo transfer with either GnRH agonist (n = 22) or GnRH antagonist (n = 20) protocols from 2010 to 2011 were collected during oocyte retrieval. SCF concentrations of serum and FF were assessed by sandwich enzyme immunoassay using ELISA Kit for SCF kid. Serum UCN1 concentration were measured using commercially available enzyme-linked immunosorbent assay. Concentrations of serum UCN1, serum and FF SCF were similar in the two groups. The serum SCF levels correlated strongly with the follicular SCF levels (r = 0.770, p < 0.001). The mean implantation rate, biochemical and clinical pregnancy rate and live birth rate per cycle were also similar in the groups. These observations suggest that there is no significant difference in follicular microenvironment in terms of SCF and UCN1 between agonist and antagonist protocols.en_US
dc.identifier.doi10.1007/s00404-013-2804-1
dc.identifier.endpage1422en_US
dc.identifier.issn0932-0067
dc.identifier.issn1432-0711
dc.identifier.issue6en_US
dc.identifier.pmid23801011en_US
dc.identifier.scopus2-s2.0-84889100305en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1417en_US
dc.identifier.urihttps://doi.org/10.1007/s00404-013-2804-1
dc.identifier.urihttps://hdl.handle.net/11616/96292
dc.identifier.volume288en_US
dc.identifier.wosWOS:000326884700038en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAssisted reproductionen_US
dc.subjectOocyte maturationen_US
dc.subjectSCFen_US
dc.subjectUCN1en_US
dc.subjectGnRH agonisten_US
dc.subjectGnRH antagonisten_US
dc.titleEffect of ovarian stimulation with recombinant follicle-stimulating hormone, gonadotropin-releasing hormone agonist and antagonists, on follicular fluid stem cell factor and serum urocortin 1 levels on the day of oocyte retrievalen_US
dc.typeArticleen_US

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