Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties

dc.contributor.authorDoğan, Murat
dc.contributor.authorTaşkın, Duygu
dc.contributor.authorErmanoğlu, Mizgin
dc.contributor.authorArabacı, Turan
dc.date.accessioned2022-12-19T07:49:18Z
dc.date.available2022-12-19T07:49:18Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, antioxidant and antiproliferative properties of ‘‘Achillea phrygia’’ were investigated. Since the antioxidant and antiproliferative activity of B sub-extract from plant’s chloroform extract is higher than other extracts, B sub-extract of Achillea phrygia was used in the preparation of nanoparticles. Characterization of nanoparticles was made, antiproliferative activities and IC50 values of nanoparticles and only chloroform extract was calculated by cell culture studies and XTT cell viability test. According to the results, it was observed that the extract-loaded chitosan nanoparticles had a strong antiproliferative activity in both MCF 7 and HT29 cells. The results of this study support that bioactive extract of the Achillea phrygia plant can be prepared as an herbal medicine candidate by preparing formulations with biopolymers and being investigated in cancer studies.en_US
dc.identifier.citationDOĞAN M, TAŞKIN D, ERMANOĞLU M, ARABACI T (2022). Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. Cumhuriyet Science Journal, 43(1), 27 - 32. 10.17776/csj.1056496en_US
dc.identifier.doi10.17776/csj.1056496en_US
dc.identifier.endpage32en_US
dc.identifier.issn2587-2680
dc.identifier.issn2587-246X
dc.identifier.issue1en_US
dc.identifier.startpage27en_US
dc.identifier.trdizinid1114635en_US
dc.identifier.urihttps://doi.org/10.17776/csj.1056496
dc.identifier.urihttps://hdl.handle.net/11616/85824
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1114635
dc.identifier.volume43en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofCumhuriyet Science Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleCharacterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Propertiesen_US
dc.typeArticleen_US

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