Incidence and clinical presentation of portal vein thrombosis in cirrhotic patients

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dc.authoridCagin, Yasir Furkan/0000-0002-2538-857X
dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoriderdogan, mehmet ali/0000-0002-1713-5695
dc.authorwosidCagin, Yasir Furkan/ABI-2709-2020
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosiderdogan, mehmet ali/ABI-4675-2020
dc.contributor.authorCagin, Yasir Furkan
dc.contributor.authorAtayan, Yahya
dc.contributor.authorErdogan, Mehmet Ali
dc.contributor.authorDagtekin, Firat
dc.contributor.authorColak, Cemil
dc.date.accessioned2024-08-04T20:42:43Z
dc.date.available2024-08-04T20:42:43Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBACKGROUND: Portal vein thrombosis (PVT) is due to many risk factors, but its pathogenesis is still not clearly understood. To identify the risk factors for PVT, we analyzed the clinical characteristics and complications associated with PVT in cirrhotic patients. METHODS: We studied patients with liver cirrhosis who were admitted to our unit from April 2009 to December 2014. The patients were divided into the PVT and non-PVT groups, and were compared by variables including gender, age, the etiology of cirrhosis, stage of cirrhosis, complications, imaging, and treatment. RESULTS: PVT was found in 45 (9.8%) of 461 cirrhotic patients admitted to our hospital. Most patients (45.9%) had hepatitis B virus (HBV)-related cirrhosis, with a similar distribution of etiologies between the groups. However, there was no positive relationship between PVT and etiologies of cirrhosis. Most patients (71.5%) were in the stage of hepatic decompensation. No statistically significant differences were found in complications including esophageal varices, ascites, and hepatic encephalopathy between the groups. However, there was a significant positive correlation between hepatocellular carcinoma (HCC) and PVT (P<0.01). In 30 patients with PVT, thrombosis occurred in the portal vein and/or portal branches, 37.8% were diagnosed on ultrasound. CONCLUSIONS: The incidence of PVT was 9.8%, mainly in patients with HBV-related cirrhosis. The development of PVT was associated with the severity of liver disease and HCC.en_US
dc.identifier.doi10.1016/S1499-3872(16)60092-9
dc.identifier.endpage503en_US
dc.identifier.issn1499-3872
dc.identifier.issn2352-9377
dc.identifier.issue5en_US
dc.identifier.pmid27733319en_US
dc.identifier.scopus2-s2.0-84992358957en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage499en_US
dc.identifier.urihttps://doi.org/10.1016/S1499-3872(16)60092-9
dc.identifier.urihttps://hdl.handle.net/11616/97547
dc.identifier.volume15en_US
dc.identifier.wosWOS:000385902900006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofHepatobiliary & Pancreatic Diseases Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectportal vein thrombosisen_US
dc.subjectcirrhosisen_US
dc.subjectclinical presentationen_US
dc.titleIncidence and clinical presentation of portal vein thrombosis in cirrhotic patientsen_US
dc.typeArticleen_US

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