Cerebral metastasis of mucoepidermoid carcinoma as the first clinical presentation: Detailed immunohistochemical evaluation

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dc.authorscopusid24490752500
dc.authorscopusid14524170200
dc.authorscopusid24490605200
dc.authorscopusid56108998400
dc.contributor.authorHaltaş H.
dc.contributor.authorBozda? Z.
dc.contributor.authorEngjn Aydin N.
dc.contributor.authorMizrak B.
dc.date.accessioned2024-08-04T20:00:41Z
dc.date.available2024-08-04T20:00:41Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractMucoepidermoid carcinoma (MEC) is known as a lowgrade malignant tumor. Lymph node and distant metastases are only seen in the high grade variant of MEC. The patient, 52-year-old male, had progressive vision loss, urinary incontinence and weakness at the left side at first physical examination. Computed tomography scan demonstrated 4×3×4 cm mass at parafalcian region in the brain and an additional 2×2 cm mass at right lung field. The resected mass in the brain was 4.5 cm in diameter, solid, necrotic, pale gray tissue with irregular borders. Microscopically the tumor was composed of squamoid, intermediate and glandular cells. Mucicarmine, PAS-Alcian blue, carcinoembryonic antigen-monoclonal (CEA-M), cytokeratin 7 and 18 staining revealed glandular cells to whereas cytokeratin 8 was focally expressed in squamoid cells. Cytokeratin 20 and c-erb-B2 were negative in all of the tumor cells. This case is a low grade MEC metastasis which emphasizes the malignant potential of these tumors.en_US
dc.identifier.endpage86en_US
dc.identifier.issn1019-3103
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-48649093426en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://hdl.handle.net/11616/90930
dc.identifier.volume38en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectImmunohistochemistryen_US
dc.subjectMetastasisen_US
dc.subjectMucoepidermoid carcinomaen_US
dc.titleCerebral metastasis of mucoepidermoid carcinoma as the first clinical presentation: Detailed immunohistochemical evaluationen_US
dc.typeArticleen_US

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