Conducting polymers with benzothiadiazole and benzoselenadiazole units for biosensor applications
Küçük Resim Yok
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Sa
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Poly(4,7-di(2,3)-dihydrothienol[3,4-b][1,4]dioxin-5-yl-benzo[1,2,5]thiadiazole) (PBDT) and poly(4,7-di(2,3)-dihydrothienol[3,4-b][1,4]dioxin-5-yl-2,1,3-benzoselenadiazole) (PESeE) were electrochemically deposited on graphite electrodes and used as immobilization matrices for biosensing studies. After electrochemical deposition of the polymeric matrices, glucose oxidase (GOx) was immobilized on the modified electrodes as the model enzyme. In the biosensing studies, the decrease in oxygen level as a result of enzymatic reaction was monitored at -0.7 V vs Ag/AgCl (3.0 M KCl) and correlated with substrate concentration. The biosensor was characterized in terms of several parameters such as operational and storage stabilities, kinetic parameters (K-m and I-max) and surface morphologies. The biosensor was tested on real human blood serum samples. (C) 2011 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Enzyme immobilization, Conducting polymer, Biosensor, Surface modification
Kaynak
Sensors and Actuators B-Chemical
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
158
Sayı
1
