Plasma viscosity and mean platelet volume in patients undergoing coronary angiography

Basit Öğe Kaydı
dc.authoridKilinc, Evren/0000-0002-1697-6580
dc.authoridten Cate, Hugo/0000-0001-7796-4463
dc.authorwosidCate, H./ITU-6903-2023
dc.authorwosidKutlusoy, Ergun/ABB-9017-2020
dc.authorwosidCate, Hugo ten/AAM-4000-2021
dc.authorwosidKilinc, Evren/A-7409-2011
dc.contributor.authorSenen, Kubilay
dc.contributor.authorTopal, Ergun
dc.contributor.authorKilinc, Evren
dc.contributor.authorten Cate, Hugo
dc.contributor.authorTek, Ibrahim
dc.contributor.authorKarakoc, Yunus
dc.contributor.authorYetkin, Ertan
dc.date.accessioned2024-08-04T20:32:17Z
dc.date.available2024-08-04T20:32:17Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Markers of platelet activation and haemorrheological indices have been demonstrated to play a role in the pathophysiology of atherosclerosis and cardiovascular events. In this study, we aimed at investigate the association between plasma viscosity and platelet indices in patients undergoing coronary angiography. Materials and methods: Three hundred and eighty four consecutive patients scheduled to undergo coronary angiography were included in the study. Prior to coronary angiography, blood samples were withdrawn to determine routine biochemical markers, blood cell analyses and viscosity measurements. According to the results of coronary angiography, patients were classified either in a subgroup with coronary artery disease (CAD; 1 or more stenoses > 50%) or normal coronary arteries (NCA; no stenoses or < 50%). Results: There was a statistically significant correlation between plasma viscosity and mean platelet volume levels in all patients undergoing coronary angiography (r = 0.199, p < 0.001). Additionally, when correlation analysis was performed within each group, plasma viscosity significantly correlated with MPV both in patients with CAD (r = 0.18, p = 0.004) and in patients with NCAs (r = 0.272, p = 0.002). Linear regression analysis revealed that plasma viscosity was positively associated with MPV while platelet number was inversely but significantly associated with MPV. Conclusion: We have shown for the first time that MPV correlates with plasma viscosity in patients undergoing coronary angiography, suggesting a relation with plasma proteins and activation of circulating platelets or peripheral consumption of platelets. To evaluate this relation further controlled studies also in patients with acute coronary syndromes are warranted.en_US
dc.identifier.doi10.3233/CH-2010-1249
dc.identifier.endpage41en_US
dc.identifier.issn1386-0291
dc.identifier.issn1875-8622
dc.identifier.issue1en_US
dc.identifier.pmid20134091en_US
dc.identifier.scopus2-s2.0-76649141186en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage35en_US
dc.identifier.urihttps://doi.org/10.3233/CH-2010-1249
dc.identifier.urihttps://hdl.handle.net/11616/94978
dc.identifier.volume44en_US
dc.identifier.wosWOS:000275136400005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIos Pressen_US
dc.relation.ispartofClinical Hemorheology and Microcirculationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMean platelet volumeen_US
dc.subjectplasma viscosityen_US
dc.subjectcoronary artery diseaseen_US
dc.subjectplatelet activationen_US
dc.titlePlasma viscosity and mean platelet volume in patients undergoing coronary angiographyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu