The predictors of mortality in non-traumatic splenectomies

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dc.authorscopusid15053759700
dc.contributor.authorSimsek A.
dc.date.accessioned2024-08-04T19:59:05Z
dc.date.available2024-08-04T19:59:05Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground – There are quite a few studies examining prognostic factors in non-traumatic splenectomies compared to traumatic ones. Objective – This study aimed to evaluate the predictors of mortality in patients who underwent splenectomy for non-traumatic spleen diseases. Methods – Medical records of the patients, who had undergone total splenectomy for non-traumatic spleen diseases at a tertiary center between January 2009 and December 2019, were retrospectively reviewed. Exclusion criteria included patients younger than 18 years of age, partial splenectomies, splenectomies applied to facilitate surgery for malignancy on contiguous organs, and splenectomies performed during liver transplantation. Iatrogenic splenic injuries were regarded as trauma and these cases were also excluded. Results – The current study included 98 patients. Nine (9.2%) patients died. In univariate analysis, age, the presence of hematological neoplasia, hematocrit, hemoglobin, white blood cell counts, neutrophil-to-lymphocyte ratio, indications for splenectomy, application of emergency surgery, surgical technique, and transfusion of blood components were all significantly associated with mortality. In multivariate analysis, the presence of hematological malignancy [P=0.072; OR=7.17; (CI: 0.386–61.56)], the application of emergency surgery [P=0.035; OR=8.33; (CI: 1.165–59.595)] and leukocytosis [P=0.057; OR=1.136; (CI: 0.996–1.296)] were found to be positively associated with mortality. Conclusion – Hematologic neoplasia, emergency surgery, and leukocytosis were the independent predictors of mortality in patients, who were operated on for non-traumatic spleen diseases. A thorough preoperative evaluation, early therapeutic intervention, and advanced surgical techniques are important and can serve to minimize complications and mortality in case of inevitable splenectomy. Immunological research can provide new therapeutic opportunities that may impact positively on patients by minimizing morbidity and mortality. © 2020, IBEPEGE - Inst. Bras. Estudos Pesquisas Gastroent. All rights reserved.en_US
dc.identifier.doi10.1590/S0004-2803.202000000-80
dc.identifier.endpage465en_US
dc.identifier.issn0004-2803
dc.identifier.issue4en_US
dc.identifier.pmid33331477en_US
dc.identifier.scopus2-s2.0-85097836198en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage459en_US
dc.identifier.urihttps://doi.org/10.1590/S0004-2803.202000000-80
dc.identifier.urihttps://hdl.handle.net/11616/90354
dc.identifier.volume57en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIBEPEGE - Inst. Bras. Estudos Pesquisas Gastroent.en_US
dc.relation.ispartofArquivos de Gastroenterologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEmergenciesen_US
dc.subjectHematologic neoplasmsen_US
dc.subjectLeukocytosisen_US
dc.subjectRisk factorsen_US
dc.subjectSplenectomy, mortalityen_US
dc.subjectSplenic diseasesen_US
dc.titleThe predictors of mortality in non-traumatic splenectomiesen_US
dc.title.alternativeOs preditores da mortalidade em esplenectomias não traumáticasen_US
dc.typeArticleen_US

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