Bingöl bölgesinde endemik guatr olgularında tiroid kanseri görülme sıklığı
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Dosyalar
Tarih
2013
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi Tıp Fakültesi Dergisi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Tiroid kanserleri endokrin organların en sık görülen kanser türü olup, tüm kanser türlerinin %1’ini oluşturur. Tiroid kanserlerinin görülme sıklığı özellikle endemik iyot yetersizliğinin ve guatrın olduğu bölgelerde artmaktadır. Bu çalışmanın amacı iyot eksikliği bölgesi olan Bingöl ilinde opere edilen nodüler guatr olgularında tiroid kanseri görülme sıklığını ve kanser tiplerini araştırmaktır.
Gereç ve Yöntemler: Bingöl Devlet Hastanesi patoloji bölümüne 2004-2012 yılları arasında gönderilen tiroid operasyon materyallerine ait patoloji raporları retrospektif olarak arşivden tarandı. 8 yıl içerisinde gönderilen toplam 1275 nodüler guatr olgusuna ait postoperatif histopatolojik bulgular değerlendirildi.
Bulgular: Toplam 1275 olgunun 1130’u (%88,6) kadın, 145’i (%11,4) erkek idi. En genç hasta 13, en yaşlı hasta 85 yaşında olup yaş ortalaması 42,7±11,4 idi. Histopatolojik incelemede 1073 (%84,2) olguda nodüler hiperplazi, 12 (%0,9) olguda diffüz hiperplazi, 57 (%4,5) olguda lenfositik tiroidit, 133 (%10,4) olguda ise tiroid tümörü saptandı. 133 tümör olgusunun 33’ü (%25) benign, 100’ü (%75) malign idi. Kanser tipi olarak 88 (%66,1) olguda papiller karsinom, 11 (%8,2) olguda folliküler karsinom, 1 (%0,7) olguda ise medüller karsinom tespit edildi.
Sonuç: İyot eksikliğinin endemik olarak görüldüğü Bingöl ilinde opere edilen nodüler guatr olgularında tiroid kanseri görülme sıklığı %7,8 olup, kanser tiplerine göre de en sık papiller tiroid karsinomu görülmektedir.
Objective: Thyroid cancer is the most common malignancy of the endocrine organs, and it accounts for 1% of all cancers. Its incidence increases in sites of endemic iodine deficiency and goiter. The aim of this study is to investigate the thyroid cancer incidence and types in nodular goiter cases operated in the city of Bingol, which is an iodine deficiency region. Material and Methods: The pathology reports of thyroid surgical materials which were sent to Bingöl Government Hospital pathology department were screened retrospectively from the archives between the years 2004-2012. Postoperative histopathologic examinations of 1275 cases that received nodular goiters diagnosis were evaluated in 8 years. Results: 1130 (88.6%) of 1275 cases female and 145 (11.4%) were male. The youngest patient was 13 and the oldest patient was 85 years old and the average age is 42,7±11,4. Histopathological examination of 1073 (84.2%) cases of nodular hyperplasia, 12 (0.9%) cases of diffuse hyperplasia, 57 (4.5%) cases of lymphocytic thyroiditis, 133 (10.4%) patients had thyroid tumors. The 133 tumors on the 33 (25%) cases benign, 100 (75%) cases were malign. As a type of cancer 88 (66.1%) cases papillary carcinoma, 11 (8.2%) cases follicular carcinoma, 1 (0.7%) case were medullary carcinoma. Conclusions: Iodine deficiency area in the province of Bingöl in patients with nodular goiter who underwent surgery for thyroid cancer rate of 7.8% and most cancers is seen as a type of thyroid papillary carcinoma.
Objective: Thyroid cancer is the most common malignancy of the endocrine organs, and it accounts for 1% of all cancers. Its incidence increases in sites of endemic iodine deficiency and goiter. The aim of this study is to investigate the thyroid cancer incidence and types in nodular goiter cases operated in the city of Bingol, which is an iodine deficiency region. Material and Methods: The pathology reports of thyroid surgical materials which were sent to Bingöl Government Hospital pathology department were screened retrospectively from the archives between the years 2004-2012. Postoperative histopathologic examinations of 1275 cases that received nodular goiters diagnosis were evaluated in 8 years. Results: 1130 (88.6%) of 1275 cases female and 145 (11.4%) were male. The youngest patient was 13 and the oldest patient was 85 years old and the average age is 42,7±11,4. Histopathological examination of 1073 (84.2%) cases of nodular hyperplasia, 12 (0.9%) cases of diffuse hyperplasia, 57 (4.5%) cases of lymphocytic thyroiditis, 133 (10.4%) patients had thyroid tumors. The 133 tumors on the 33 (25%) cases benign, 100 (75%) cases were malign. As a type of cancer 88 (66.1%) cases papillary carcinoma, 11 (8.2%) cases follicular carcinoma, 1 (0.7%) case were medullary carcinoma. Conclusions: Iodine deficiency area in the province of Bingöl in patients with nodular goiter who underwent surgery for thyroid cancer rate of 7.8% and most cancers is seen as a type of thyroid papillary carcinoma.
Açıklama
[Turgut Özal Tıp Merkezi Dergisi, (2013).20 (4)]
Anahtar Kelimeler
Guatr, İyot Eksikliği, Tiroid Kanseri, Goiter, Iodine Deficiency, Thyroid Cancer
Kaynak
Turgut Özal Tıp Merkezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
20
Sayı
4
Künye
Üçer, Ö.,(2013).Bingöl bölgesinde endemik guatr olgularında tiroid kanseri görülme sıklığı.Turgut Özal Tıp Merkezi Dergisi, 20 (4).305-308 ss.
