Chemical composition and antimicrobial activity of an apolar extract from Lactuca serriola L. leaves

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dc.authoridUnver, Tuba/0000-0002-8655-2716
dc.authorwosidUnver, Tuba/ABI-6440-2020
dc.contributor.authorUnver, Tuba
dc.contributor.authorGurhan, Ismet
dc.date.accessioned2024-08-04T20:55:56Z
dc.date.available2024-08-04T20:55:56Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractLactuca serriola L. is an annual herbaceous plant species belonging to the Asteraceae family, called Prickly lettuce, Wild lettuce, and Jagged lettuce. L. serriola grows on grassy and rocky slopes in many regions in Europe, Asia, Australia, Africa, and North, Central and South America. The plant is used as a natural pharmaceutical agent in primary health care due to its analgesic, anti-inflammatory, antibacterial, and antioxidant properties, which are attributed to the compounds it contains. However, this is the first study demonstrating the antimicrobial activity of L. serriola essential oil. In this study, L. serriola essential oil was obtained by hydrodistillation of plant leaves and analyzed by Gas Chromatography -Mass Spectrometry (GS -MS); subsequently, antimicrobial properties of the essential oil were evaluated using agar dilution and broth microdilution methods. As a result of the GS -MS analysis, hexadecanoic acid, oleic acid, myristic acid, hexahydrofarnesyl acetone, beta-ionone, and n-tetradecyl butanoate were found as dominant components in the plant essential oil with the rate of 6.61%, 4.84%, 2.05, 1.55%, 1.3%, and 1.09% (v/v), respectively. The MIC value of L. serriola essential oil against Enterobacter aerogenes, Staphylococcus aureus , Pseudomonas aeruginosa , Candida albicans , and C andida tropicalis was found to be 0.94 mu LmL -1 , and MIC values were determined as 1.87 mu LmL -1 and 0.47 mu LmL -1 against Klebsiella pneumonia and Candida parapsilosis , respectively. These results have opened a new horizon regarding the usability of L. serriola essential oil as a pharmacological therapeutic antibacterial and antifungal agent.en_US
dc.identifier.doi10.1016/j.bse.2024.104832
dc.identifier.issn0305-1978
dc.identifier.issn1873-2925
dc.identifier.scopus2-s2.0-85191310586en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1016/j.bse.2024.104832
dc.identifier.urihttps://hdl.handle.net/11616/101950
dc.identifier.volume114en_US
dc.identifier.wosWOS:001235167900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofBiochemical Systematics and Ecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLactuca serriolaen_US
dc.subjectPhytochemical compositionen_US
dc.subjectAntibacterial activityen_US
dc.subjectAntifungal activityen_US
dc.subjectTherapyen_US
dc.subjectPharmaceutical agenten_US
dc.titleChemical composition and antimicrobial activity of an apolar extract from Lactuca serriola L. leavesen_US
dc.typeArticleen_US

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