Impact of serum and follicular vitamin d levels on assisted reproductive techniques outcome
Küçük Resim Yok
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SCI PRINTERS & PUBL INC, PO DRAWER 12425 8342 OLIVE BLVD, ST LOUIS, MO 63132 USA
Erişim Hakkı
info:eu-repo/semantics/restrictedAccess
Özet
OBJECTIVE: To compare vitamin D levels in the serum and follicular fluids of in vitro fertilization (IVF) patients with regard to their pregnancy outcomes.
STUDY DESIGN: This study enrolled 170 female patients (20-44 years old) who underwent intracytoplasmic sperm injection (ICSI) cycles between February 2015 and February 2016. The serum vitamin D was isolated by centrifugation. The follicular fluid samples were centrifuged and the supernatant was evaluated after the oocyte puncture procedure.
RESULTS: Fifty-six patients had clinical pregnancies and 106 did not, and we did not find any statistically significant differences between these 2 groups in their basic or cycle characteristics. The basal follicle-stimulating hormone level was significantly lower in the pregnant group (p=0.003). A significant difference was detected in the serum vitamin D, and the follicular vitamin D concentrations were higher in the pregnant group (p=0.01 and p=0.003, respectively). There was a significant linear correlation between the 25-hydroxy vitamin D levels in the serum and follicular fluid (r=0.77, p<0.001).
CONCLUSION: High vitamin D levels can improve the implantation rate and IVF outcome. The serum vitamin D level should be determined prior to IVF/ICSI cycles and supplemented if an insufficiency is established.
Açıklama
Anahtar Kelimeler
Ivf Outcomes, Embryo Qualıty, D Defıcıency, Art Cycles, Hox Genes, Fluıd, Pregnancy, Fertılızatıon, Fertılıty, Female
Kaynak
Journal of reproductıve medıcıne
WoS Q Değeri
Scopus Q Değeri
Cilt
63
Sayı
5-6
Künye
Tuncay, G. Taşkapan, Ç. (2018). Impact of serum and follicular vitamin d levels on assisted reproductive techniques outcome. Cilt:63 Sayı:5-6, 305-310 ss.
