Amniotic fluid urocortin-1 concentrations for the prediction of preterm delivery

Basit Öğe Kaydı
dc.authoridCelik, ebru/0000-0002-0774-4294
dc.authoridDüz, Senem Arda/0000-0002-9325-7993
dc.authoridKaraer, Abdullah/0000-0002-2010-6211
dc.authoridTURKCUOGLU, ILGIN/0000-0002-8342-1956
dc.authorwosidÖzerol, İbrahim Halil/ABI-8015-2020
dc.authorwosidCelik, ebru/X-4343-2019
dc.authorwosidDüz, Senem Arda/ABE-2480-2020
dc.authorwosidKaraer, Abdullah/ABI-4667-2020
dc.contributor.authorKaraer, Abdullah
dc.contributor.authorCelik, Ebru
dc.contributor.authorCelik, Onder
dc.contributor.authorSimsek, Omer Yavuz
dc.contributor.authorOzerol, Ibrahim Halil
dc.contributor.authorYilmaz, Ercan
dc.contributor.authorTurkcuoglu, Ilgin
dc.date.accessioned2024-08-04T20:37:43Z
dc.date.available2024-08-04T20:37:43Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim The aim of this study was to analyze whether urocortin-1 concentration in midtrimester amniotic fluid could serve as an indicative marker of preterm labor. Material and Methods A retrospective cohort study was conducted. Urocortin-1 concentrations in midtrimester amniotic fluid were measured in 22 pregnant women with preterm deliveries and 45 women who delivered at term using enzyme-linked immunosorbent assay. Results The median amniotic fluid urocortin-1 concentration was significantly lower in the women with preterm birth (40.06pg/mL; range, 13.77-67.58pg/mL) than in the women who gave birth at term (49.56pg/mL; range, 26.25-175.9pg/mL; P=0.022). The result of receiver-operator curve analysis indicates that an amniotic fluid urocortin-1 concentration57.88pg/mL had an area under the curve of 0.673 (95% confidence interval, 0.55-0.78; P=0.01) with a sensitivity of 81.8%, specificity of 40.0%, positive predictive value of 40%, and a negative predictive value of 82% in identifying which of the patients subsequently delivered prematurely. Conclusions These results suggest that low urocortin-1 concentration in midtrimester amniotic fluid could be used as an indicative marker of preterm birth.en_US
dc.description.sponsorshipScientific Research Projects Unit of Our Institution [2011/72]en_US
dc.description.sponsorshipThis work was funded by the Scientific Research Projects Unit of Our Institution (project no: 2011/72). We wish to thank Birol EPIK for technical assistance with the ELISA analysis.en_US
dc.identifier.doi10.1111/jog.12054
dc.identifier.endpage1241en_US
dc.identifier.issn1341-8076
dc.identifier.issn1447-0756
dc.identifier.issue7en_US
dc.identifier.pmid23803006en_US
dc.identifier.scopus2-s2.0-84880296961en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1236en_US
dc.identifier.urihttps://doi.org/10.1111/jog.12054
dc.identifier.urihttps://hdl.handle.net/11616/96141
dc.identifier.volume39en_US
dc.identifier.wosWOS:000320933300003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Obstetrics and Gynaecology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectamniotic fluiden_US
dc.subjectpreterm deliveryen_US
dc.subjecturocortin-1en_US
dc.titleAmniotic fluid urocortin-1 concentrations for the prediction of preterm deliveryen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu