Anthracene derivatives of Asphodelaceae plants and their biological activities

Basit Öğe Kaydı
dc.contributor.authorOzgen, Ridvan
dc.contributor.authorKuruuzum-Uz, Ayse
dc.date.accessioned2026-04-04T13:37:27Z
dc.date.available2026-04-04T13:37:27Z
dc.date.issued2025
dc.departmentİnönü Üniversitesi
dc.description.abstractMedicinal plants are the most important resources for obtaining and developing new drugs and have recently attracted more pharmacological and industrial interest. Anthracene derivatives are one of the important phenolic compounds that naturally occur in plants. They exhibit bioactivities such as anticancer, antimicrobial, immune-suppressive, antioxidant, antipyretic, anti-inflammatory, and laxative effects. Anthraquinones and anthraquinones dimers are considered important chemotaxonomic markers for plants in the family Asphodelaceae. Many anthracenes and anthracene derivatives from Asphodelaceae taxa were known for their biological activity demonstrated in in vitro and in vivo biological assays. In this study, research published between 1963 and 2025 on anthracenes from Asphodelaceae taxa and their biological activities was analyzed by searching scientific databases such as PubMed, Scopus, Google Scholar, Web of Knowledge, and other web sources. As a result of these analyses, preanthraquinones (1-18), anthrones (19-43), anthraquinones (44-91), phenylanthraquinones (92-119), and anthraquinone dimers (120-162) and their biological activities are summarized, providing an overview of naturally bioactive anthracenes from Asphodelaceae that could serve as potential leads for new drug discovery.
dc.description.sponsorshipScientific and Technological Research Council of Turkiye (TUBITAK)
dc.description.sponsorshipOpen access funding provided by the Scientific and Technological Research Council of Turkiye (TUBITAK).
dc.identifier.doi10.1007/s11101-025-10141-6
dc.identifier.endpage3885
dc.identifier.issn1568-7767
dc.identifier.issn1572-980X
dc.identifier.issue5
dc.identifier.orcid0000-0003-3373-4759
dc.identifier.orcid0000-0002-2505-027X
dc.identifier.scopus2-s2.0-105016158372
dc.identifier.scopusqualityQ1
dc.identifier.startpage3829
dc.identifier.urihttps://doi.org/10.1007/s11101-025-10141-6
dc.identifier.urihttps://hdl.handle.net/11616/109828
dc.identifier.volume24
dc.identifier.wosWOS:001570473100001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofPhytochemistry Reviews
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250329
dc.subjectAsphodelaceae
dc.subjectAnthraquinone derivatives
dc.subjectBiological activity
dc.subjectCytotoxicity
dc.subjectAntiplasmodial activity
dc.titleAnthracene derivatives of Asphodelaceae plants and their biological activities
dc.typeReview

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