The relationship between serum trace element changes and visual function in heavy smokers

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dc.authorwosidUz, Efkan/B-2943-2016
dc.contributor.authorUz, E
dc.contributor.authorSahin, S
dc.contributor.authorHepsen, IF
dc.contributor.authorVar, A
dc.contributor.authorSogut, S
dc.contributor.authorAkyol, O
dc.date.accessioned2024-08-04T20:13:20Z
dc.date.available2024-08-04T20:13:20Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The aim of this prospective study was to evaluate serum manganese (Mn), zinc (Zn) and copper (Cu) levels and visual functions including visual acuity, colour vision, pattern visual evoked potentials (PVEPs), and contrast sensitivity in heavy smokers and to compare these with the equivalent levels and functions in non-smokers. Methods: Data were recorded in 24 healthy, chronic and heavy cigarette smokers and 16 healthy, non-smoking control subjects. Serum Zn, Cu and Mn concentrations in all subjects were measured by atomic absorption spectrophotometry. Results: Both study and control subjects had normal visual acuity and colour vision. Pattern visual evoked potentials were normal in all study and control subjects. Contrast sensitivity was significantly reduced in heavy smokers compared to non-smokers (p<0.023), despite the fact that central vision and PVEP responses were not affected. Mean serum Mn and Zn levels were significantly lower in smokers than in non-smokers (p<0.0001 and p<0.005, respectively). Conclusions: Reduced contrast sensitivity values associated with low levels of serum Mn and Zn, which function as cofactors of superoxide dismutase in erythrocyte and other nucleated cells, suggest a possible role of trace elements in smoking-induced early retinal toxicity.en_US
dc.identifier.doi10.1034/j.1600-0420.2003.00032.x
dc.identifier.endpage164en_US
dc.identifier.issn1395-3907
dc.identifier.issue2en_US
dc.identifier.pmid12752055en_US
dc.identifier.scopus2-s2.0-0038296149en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage161en_US
dc.identifier.urihttps://doi.org/10.1034/j.1600-0420.2003.00032.x
dc.identifier.urihttps://hdl.handle.net/11616/93551
dc.identifier.volume81en_US
dc.identifier.wosWOS:000182833200012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofActa Ophthalmologica Scandinavicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmanganeseen_US
dc.subjectzincen_US
dc.subjectcopperen_US
dc.subjectcontrast sensitivityen_US
dc.subjectsmokingen_US
dc.subjectvisual functionen_US
dc.titleThe relationship between serum trace element changes and visual function in heavy smokersen_US
dc.typeArticleen_US

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