Acute effect of moderate and high-intensity interval exercises on asprosin and BDNF levels in inactive normal weight and obese individuals

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dc.authoridSilva, Ana Filipa/0000-0002-1772-1272
dc.authoridClemente, Filipe Manuel/0000-0001-9813-2842
dc.authoridÖztürk, Deniz/0000-0002-9939-5895
dc.authoridEken, Özgür/0000-0002-5488-3158
dc.authoridNobari, Hadi/0000-0001-7951-8977
dc.authorwosidSilva, Ana Filipa/J-1249-2019
dc.authorwosidClemente, Filipe Manuel/G-2625-2012
dc.authorwosidÖztürk, Deniz/R-3263-2019
dc.authorwosidEken, Özgür/ABE-8274-2020
dc.authorwosidNobari, Hadi/AAO-9721-2021
dc.contributor.authorCeylan, Halil Ibrahim
dc.contributor.authorOzturk, Mehmet Ertugrul
dc.contributor.authorOzturk, Deniz
dc.contributor.authorSilva, Ana Filipa
dc.contributor.authorAlbayrak, Mevlut
dc.contributor.authorSaygin, Ozcan
dc.contributor.authorEken, Ozgur
dc.date.accessioned2024-08-04T20:53:41Z
dc.date.available2024-08-04T20:53:41Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study aimed to examine the acute effects of moderate-intensity aerobic and high-intensity interval exercise protocols on Asprosin and Brain-Derived Neurotrophic Factor (BDNF) levels in inactive normal weight and obese individuals. A total of 20 male individuals aged 18-65 years, ten normal weight (NW) (Body Mass Index (BMI): 18.5-24.99 kg/m(2)) and 10 obese (Ob) (BMI: 24.99-35.00 kg/m(2)) participated in this study, voluntarily. Moderate aerobic exercise (AE) (main circuit 30 min, between 40 and 59% of Heart Rate Reserve: HRR) and High-Intensity Interval exercise (HIIE) running protocols (main circuit 20 min, between 75 and 90% of the HRR for 1 min*10 times, and 1-min active rest at 30% of the HRR) was applied to the volunteer participants in the morning hours (08.00-10.00 a.m.), following the night fasting (at least 8-10 h) for at least 3 days between each other. Blood samples were collected from the participants before and immediately after each exercise protocol, and serum asprosin and BDNF hormone levels were determined by Enzyme-Linked Immunosorbent Assay method. Basal serum asprosin was found to be significantly higher in the Ob group compared to the NW group (p < .001), while the basal serum BDNF hormone was found to be lower (p < 0.05). It was observed that the serum asprosin level of both groups decreased significantly after both AE and HIIE protocols (p < 0.05). In addition, there was a significantly higher decrease in serum asprosin level in the Ob group compared to the NW group after HIIE protocol. For the Ob group, serum BDNF level increased considerably after HIIE protocol compared to AE protocol (p < 0.05). Serum asprosin was found to be higher in the Ob group, while the serum BDNF was found to be lower. In addition, the acute exercises of different intensity significantly affected hormones that regulate appetite metabolism. In particular, it was observed that the HIIE protocol had a greater effect on the regulation of appetite (hunger-satiety) in the Ob group. This result can be taken into account when planning training programs for these individuals.en_US
dc.description.sponsorshipFundacao para a Ciencia e Tecnologia/Ministerio da Ciencia, Tecnologia e Ensino Superior; EU [UIDB/50008/2020]en_US
dc.description.sponsorshipThis work is funded by Fundacao para a Ciencia e Tecnologia/Ministerio da Ciencia, Tecnologia e Ensino Superior through national funds and when applicable co-funded EU funds under the project UIDB/50008/2020.en_US
dc.identifier.doi10.1038/s41598-023-34278-6
dc.identifier.issn2045-2322
dc.identifier.issue1en_US
dc.identifier.pmid37120612en_US
dc.identifier.scopus2-s2.0-85156115817en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1038/s41598-023-34278-6
dc.identifier.urihttps://hdl.handle.net/11616/101330
dc.identifier.volume13en_US
dc.identifier.wosWOS:000984763000022en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNature Portfolioen_US
dc.relation.ispartofScientific Reportsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNeurotrophic Factoren_US
dc.subjectPhysical-Exerciseen_US
dc.subjectHuman Plateletsen_US
dc.subjectHealthyen_US
dc.subjectNeuroplasticityen_US
dc.subjectPerformanceen_US
dc.subjectAdaptationsen_US
dc.subjectPlasticityen_US
dc.subjectPhysiologyen_US
dc.subjectIncreasesen_US
dc.titleAcute effect of moderate and high-intensity interval exercises on asprosin and BDNF levels in inactive normal weight and obese individualsen_US
dc.typeArticleen_US

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