Comparison of exercise capacity in COPD and other etiologies of chronic respiratory failure requiring non-invasive mechanical ventilation at home: retrospective analysis of 1-year follow-up

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dc.authoridMocin, Ozlem Yazicioglu/0000-0003-3161-6118
dc.authoridÖztaş, Selahattin/0000-0001-7658-1225
dc.authoridGungor, Gokay/0000-0003-2294-489X
dc.authoridYalçınsoy, Murat/0000-0003-3407-7359;
dc.authorwosidOzmen, Ipek/I-3449-2018
dc.authorwosidMocin, Ozlem Yazicioglu/AAY-5196-2020
dc.authorwosidÖztaş, Selahattin/HKW-7272-2023
dc.authorwosidGungor, Gokay/N-8373-2015
dc.authorwosidYalçınsoy, Murat/ABI-1421-2020
dc.authorwosidKalamanoglu Balci, Merih/D-4993-2018
dc.contributor.authorSalturk, Cuneyt
dc.contributor.authorKarakurt, Zuhal
dc.contributor.authorTakir, Huriye Berk
dc.contributor.authorBalci, Merih
dc.contributor.authorKargin, Feyza
dc.contributor.authorMocin, Ozlem Yazicioglu
dc.contributor.authorGungor, Gokay
dc.date.accessioned2024-08-04T20:41:20Z
dc.date.available2024-08-04T20:41:20Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: The objective of this study was to compare the change in 6-minute walking distance (6MWD) in 1 year as an indicator of exercise capacity among patients undergoing home non-invasive mechanical ventilation (NIMV) due to chronic hypercapnic respiratory failure (CHRF) caused by different etiologies. Methods: This retrospective cohort study was conducted in a tertiary pulmonary disease hospital in patients who had completed 1-year follow-up under home NIMV because of CHRF with different etiologies (ie, chronic obstructive pulmonary disease [COPD], obesity hypoventilation syndrome [OHS], kyphoscoliosis [KS], and diffuse parenchymal lung disease [DPLD]), between January 2011 and January 2012. The results of arterial blood gas (ABG) analyses and spirometry, and 6MWD measurements with 12-month interval were recorded from the patient files, in addition to demographics, comorbidities, and body mass indices. The groups were compared in terms of 6MWD via analysis of variance (ANOVA) and multiple linear regression (MLR) analysis (independent variables: analysis age, sex, baseline 6MWD, baseline forced expiratory volume in 1 second, and baseline partial carbon dioxide pressure, in reference to COPD group). Results: A total of 105 patients with a mean age (+/- standard deviation) of 61 +/- 12 years of whom 37 had COPD, 34 had OHS, 20 had KS, and 14 had DPLD were included in statistical analysis. There were no significant differences between groups in the baseline and delta values of ABG and spirometry findings. Both univariate ANOVA and MLR showed that the OHS group had the lowest baseline 6MWD and the highest decrease in 1 year (linear regression coefficient -24.48; 95% CI-48.74 to -0.21, P = 0.048); while the KS group had the best baseline values and the biggest improvement under home NIMV (linear regression coefficient 26.94; 95% CI-3.79 to 57.66, P = 0.085). Conclusion: The 6MWD measurements revealed improvement in exercise capacity test in CHRF patients receiving home NIMV treatment on long-term depends on etiological diagnoses.en_US
dc.identifier.doi10.2147/COPD.S91950
dc.identifier.endpage2569en_US
dc.identifier.issn1178-2005
dc.identifier.pmid26648713en_US
dc.identifier.scopus2-s2.0-84948963904en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage2559en_US
dc.identifier.urihttps://doi.org/10.2147/COPD.S91950
dc.identifier.urihttps://hdl.handle.net/11616/97072
dc.identifier.volume10en_US
dc.identifier.wosWOS:000366032100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDove Medical Press Ltden_US
dc.relation.ispartofInternational Journal of Chronic Obstructive Pulmonary Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectexercise capacityen_US
dc.subjectnon-invasive ventilationen_US
dc.subject6-minute walking testen_US
dc.subjectchronic respiratory failureen_US
dc.titleComparison of exercise capacity in COPD and other etiologies of chronic respiratory failure requiring non-invasive mechanical ventilation at home: retrospective analysis of 1-year follow-upen_US
dc.typeArticleen_US

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