Hair lead and cadmium concentrations in patients with epilepsy and migraine

Basit Öğe Kaydı
dc.authorwosidVural, Hüseyin/B-3300-2016
dc.authorwosidUz, Efkan/B-2943-2016
dc.contributor.authorSasmaz, S
dc.contributor.authorUz, E
dc.contributor.authorPinar, T
dc.contributor.authorVural, H
dc.contributor.authorEiri, M
dc.contributor.authorIlhan, A
dc.contributor.authorAkyol, Ö
dc.date.accessioned2024-08-04T20:13:20Z
dc.date.available2024-08-04T20:13:20Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractEpilepsy and migraine are neurological manifestations of neurocutaneous diseases. The studies that investigate the etiology of these manifestations may illuminate the physiopathological bases of neurocutaneous disorders. The hypothesis that the elevation of toxic trace element concentration in the brain is an important triggering factor for seizures and subsequent neuronal damage in epilepsy and migraine was investigated in this clinical prospective study. The levels of two heavy metals (lead [Pb] and cadmium [Cd]) in scalp hair were measured in patients with epilepsy (n=33) and migraine (n=40) as well as healthy control subjects (n=26). The hair concentration of these two toxic trace elements was determined by atomic absorption spectrophotometry. There was a significant increase in Pb concentration in epilepsy group when compared to both control (p<0.006) and migraine group (p<0.02). There was no difference in mean Cd concentration of hair from epilepsy, migraine patients and control groups. Therefore, no conclusive findings were obtained for Cd. Elevated Pb content in epileptic patients was accepted as being of particular importance. Our findings support the hypothesis that the elevation in Pb concentration in the scalp hair amongst patients with epilepsy may show the elevation in the brain and constitute an important triggering factor for seizures.en_US
dc.identifier.doi10.1002/nrc.10065
dc.identifier.endpage114en_US
dc.identifier.issn0893-6609
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0038555679en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage107en_US
dc.identifier.urihttps://doi.org/10.1002/nrc.10065
dc.identifier.urihttps://hdl.handle.net/11616/93562
dc.identifier.volume32en_US
dc.identifier.wosWOS:000182492100005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofNeuroscience Research Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectleaden_US
dc.subjectcadmiumen_US
dc.subjecthairen_US
dc.subjectepilepsyen_US
dc.subjectmigraineen_US
dc.subjectneurocutaneous disordersen_US
dc.titleHair lead and cadmium concentrations in patients with epilepsy and migraineen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu