Synthetic and antimicrobial studies on new gold(I) complexes of imidazolidin-2-ylidenes

Basit Öğe Kaydı
dc.authoridÖzdemir, İsmail/0000-0001-6325-0216
dc.authoridCetinkaya, Bekir/0000-0002-4551-8650
dc.authorwosidÖzdemir, İsmail/ABI-5192-2020
dc.authorwosidYalçın, H. Tansel/AAG-7526-2021
dc.contributor.authorÖzdemir, I
dc.contributor.authorDenizci, A
dc.contributor.authorÖztürk, HT
dc.contributor.authorÇetinkaya, B
dc.date.accessioned2024-08-04T20:30:42Z
dc.date.available2024-08-04T20:30:42Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractSix new 1,3-diorganylimidazolidin-2-ylidene (NHC) gold(I) complexes of the type [Au(NHC)(2)](+) (1-6), were synthesized by reacting [AuCl(PPh)(3)] with 1,3-dimesitylimidazolidin-2-ylidene or bis(1,3-dialkylimidazolidin-2-ylidene). The complexes 1-6 were fully characterized by elemental analyses and spectroscopic data. The placement of mesityl or para-substituted benzyl groups on the nitrogen atoms of the ring of the complexes leads to the particularly active antibacterial agents evaluated in this work. It is worth noting that the p-methoxybenzyl derivative (2) inhibited the growth of Pseudomona aeruginosa, Staphylococcus epidermidis, Staphylococcus aureus and Enterococcus faecalis with minimum inhibitory concentration (MIC) values of 3.12 mug ml(-1), 6.25 mug ml(-1), 3.12 mug ml(-1) and 3.12 mug ml(-1) respectively. In contrast, the analogous p-dimethylaminobenzyl derivative (3) is effective only against Escherichia coli (MIC = 3.12 mug ml(-1)). Copyright (C) 2004 John Wiley Sons, Ltd.en_US
dc.identifier.doi10.1002/aoc.668
dc.identifier.endpage322en_US
dc.identifier.issn0268-2605
dc.identifier.issn1099-0739
dc.identifier.issue7en_US
dc.identifier.scopus2-s2.0-4043076287en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage318en_US
dc.identifier.urihttps://doi.org/10.1002/aoc.668
dc.identifier.urihttps://hdl.handle.net/11616/94474
dc.identifier.volume18en_US
dc.identifier.wosWOS:000223270200003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofApplied Organometallic Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectN-heterocarbene-gold(I) complexesen_US
dc.subjectantimicrobial activityen_US
dc.subjectminimum inhibitory concentrationen_US
dc.titleSynthetic and antimicrobial studies on new gold(I) complexes of imidazolidin-2-ylidenesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu