Malondialdehyde, Glutathione, and Nitric Oxide Levels in Toxoplasma gondii Seropositive Patients

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dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridKIRAN, TUGBA RAIKA/0000-0002-3724-0249
dc.authoridKıran, Tugba Raika/0000-0002-3724-0249
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidKIRAN, TUGBA RAIKA/AAA-8224-2021
dc.authorwosidKıran, Tugba Raika/HFZ-9643-2022
dc.contributor.authorKaraman, Ulku
dc.contributor.authorCelik, Tuncay
dc.contributor.authorKiran, Tugba Raika
dc.contributor.authorColak, Cemil
dc.contributor.authorDaldal, Nilgun Ulfet
dc.date.accessioned2024-08-04T20:31:09Z
dc.date.available2024-08-04T20:31:09Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to investigate the difference in the serum malondialdehyde (MDA), glutathione (GSH), and nitric oxide (NO) levels between normal and T. gondii-infected patients. To this end, MDA, GSH, and NO levels in the sera of 37 seropositive patients and 40 participants in the control group were evaluated. In Toxoplasma ELISA, IgG results of the patient group were 1,013.0 +/- 543.8 in optical density (mean +/- SD). A statistically significant difference was found between patients and the control group in terms of MDA, GSH, and NO levels. A decrease in GSH activity was detected, while MDA and NO levels increased significantly. Consequently, it is suggested that the use of antioxidant vitamins in addition to a parasite treatment shall prove useful. The high infection vs control ratio of MDA and NO levels probably suggests the occurrence as a mechanism of tissue damage in cases of chronic toxoplasmosis. Moreover, it is recommended that the patient levels of MDA, GSH, and NO should be evaluated in toxoplasmosis.en_US
dc.identifier.doi10.3347/kjp.2008.46.4.293
dc.identifier.endpage295en_US
dc.identifier.issn0023-4001
dc.identifier.issn1738-0006
dc.identifier.issue4en_US
dc.identifier.pmid19127340en_US
dc.identifier.scopus2-s2.0-63149088988en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage293en_US
dc.identifier.urihttps://doi.org/10.3347/kjp.2008.46.4.293
dc.identifier.urihttps://hdl.handle.net/11616/94771
dc.identifier.volume46en_US
dc.identifier.wosWOS:000262298500016en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Soc Parasitology, Seoul Natl Univ Coll Medien_US
dc.relation.ispartofKorean Journal of Parasitologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectToxoplasma gondiien_US
dc.subjectmalondialdehydeen_US
dc.subjectglutathioneen_US
dc.subjectnitric oxideen_US
dc.titleMalondialdehyde, Glutathione, and Nitric Oxide Levels in Toxoplasma gondii Seropositive Patientsen_US
dc.typeArticleen_US

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