Spindle Variant Primary Diffuse Large B Cell Lymphoma of the Colon: Case Report and Literature Review

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dc.authoridTOPRAK, SERHAT/0000-0003-4136-0523
dc.authoridKaradag Soylu, Nese/0000-0002-6303-5484
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authorwosidTOPRAK, SERHAT/AAD-7854-2021
dc.authorwosidKaradag Soylu, Nese/ABH-9544-2020
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.contributor.authorToprak, Serhat
dc.contributor.authorBozdag, Zehra
dc.contributor.authorKaradag, Nese
dc.contributor.authorAkbulut, Sami
dc.date.accessioned2024-08-04T20:51:35Z
dc.date.available2024-08-04T20:51:35Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractDiffuse large B cell lymphoma (DLBCL) with spindle cell morphology is a rare variant that can be seen in extranodal regions. Because the spindle cell dominant morphology in lymphoma is extremely unusual, the diagnosis can easily be missed in many organ systems. We present a case of an 82-year-old male patient with complaints of abdominal pain and swelling. He operated with the preliminary diagnosis of cecum tumor and ileum perforation. Tumoral proliferation was observed originating from the submucosa and infiltrating the muscularis propria, with the features of mostly spindle-shaped, having round-shaped nuclei in some of the cells, and having relatively narrow cytoplasm. A panel of immunohistochemical stains were performed to rule out the possibilities of sarcoma, carcinoma, or melanoma. Diffuse strong positive reaction was observed for CD45, CD20, CD19, CD22, Pax5, and CD30. The case was reported as spindle cell variant of DLBCL based on the present findings. As far as we know, this is the first case described in the colon. We emphasize that pathologists should be reminded of lymphoma as a differential diagnosis of spindle cell tumors.en_US
dc.identifier.doi10.1007/s12029-021-00790-z
dc.identifier.endpage289en_US
dc.identifier.issn1941-6628
dc.identifier.issn1941-6636
dc.identifier.issue1en_US
dc.identifier.pmid35013921en_US
dc.identifier.scopus2-s2.0-85122873018en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage286en_US
dc.identifier.urihttps://doi.org/10.1007/s12029-021-00790-z
dc.identifier.urihttps://hdl.handle.net/11616/100416
dc.identifier.volume54en_US
dc.identifier.wosWOS:000741575100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Gastrointestinal Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColonen_US
dc.subjectDiffuse large B cell lymphomaen_US
dc.subjectSpindle cellen_US
dc.titleSpindle Variant Primary Diffuse Large B Cell Lymphoma of the Colon: Case Report and Literature Reviewen_US
dc.typeReview Articleen_US

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