Assessment of atrial electromechanical delay in patients with polycystic ovary syndrome in both lean and obese subjects

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dc.authoridTaşolar, Hakan/0000-0002-1249-7240
dc.authoridDemiröz Tasolar, Sevgi/0000-0002-9836-6814
dc.authoridPekdemir, Hasan/0000-0002-4913-5120;
dc.authorwosidTaşolar, Hakan/ABG-4466-2020
dc.authorwosidBayramoğlu, Adil/ABF-2802-2020
dc.authorwosidDemiröz Tasolar, Sevgi/KTI-6349-2024
dc.authorwosidPekdemir, Hasan/ABI-6096-2020
dc.authorwosidcetin, mustafa/AAZ-2093-2020
dc.authorwosidBayramoğlu, Adil/ABI-3122-2020
dc.contributor.authorTasolar, Hakan
dc.contributor.authorMete, Turkan
dc.contributor.authorBalli, Mehmet
dc.contributor.authorAltun, Burak
dc.contributor.authorCetin, Mustafa
dc.contributor.authorYuce, Tuncay
dc.contributor.authorTasolar, Sevgi
dc.date.accessioned2024-08-04T20:39:45Z
dc.date.available2024-08-04T20:39:45Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAimEven though polycystic ovary syndrome (PCOS) is characterized by increased inflammatory activity and insulin resistance, there is no clinical data about whether risk of atrial fibrillation are increased in these patients. We aimed to evaluate atrial conduction parameters predicting atrial involvement in this patient group. MethodsThe study population comprised 50 women 18-40 years of age who had been diagnosed with PCOS. The patients were divided into two groups: lean women (L-PCOS) with a body mass index (BMI) under 25kg/m(2) and obese women (O-PCOS) with a BMI greater than 30kg/m(2). Twenty-five age-matched lean healthy women were enrolled voluntarily as the control group. Difference between maximum and minimum P-wave duration was calculated and was defined as P-wave dispersion (Pd). Inter- and intra-atrial electromechanical delays (inter-AED, intra-AED, respectively) were measured with tissue Doppler imaging. ResultsInter- and intra-AED parameters were higher in the L-PCOS group when compared with control subjects (anova, P=0.004 and P=0.013, respectively), and were also significantly higher in the O-PCOS group compared with other groups (anova, P<0.001 for both). The regression analyses indicated that Homeostasis Model of Assessment - Insulin Resistance (HOMA-IR) (=0.603, P<0.001) and BMI (=0.379, P<0.001) were the independent predictors of inter-AED, HOMA-IR (=0.835, P<0.001) was an independent predictor of intra-AED, and BMI (=0.457, P=0.006) and the left atrial diameter (=0.350, P<0.034) were independent predictors of Pd. ConclusionConsequently, our findings provide data regarding prolonged atrial conduction parameters in PCOS patients, especially when accompanied by obesity.en_US
dc.identifier.doi10.1111/jog.12308
dc.identifier.endpage1066en_US
dc.identifier.issn1341-8076
dc.identifier.issn1447-0756
dc.identifier.issue4en_US
dc.identifier.pmid24612019en_US
dc.identifier.scopus2-s2.0-84903554672en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1059en_US
dc.identifier.urihttps://doi.org/10.1111/jog.12308
dc.identifier.urihttps://hdl.handle.net/11616/96488
dc.identifier.volume40en_US
dc.identifier.wosWOS:000333615200023en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Obstetrics and Gynaecology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectatrial electromechanical delayen_US
dc.subjectatrial fibrillationen_US
dc.subjectinsulin resistanceen_US
dc.subjectleft ventricular diastolic dysfunctionen_US
dc.subjectobesityen_US
dc.subjectpolycystic ovary syndromeen_US
dc.titleAssessment of atrial electromechanical delay in patients with polycystic ovary syndrome in both lean and obese subjectsen_US
dc.typeArticleen_US

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