Comparison of the dental serial patch test outcomes of lichen planus patients with and without oral involvement
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Deri Zuhrevi Hastaliklar Dernegi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background and Design: Lichen planus (LP) is a chronic and enflammatory cutaneous disease. Numereous diseases and agents have been accused in the etiology of LP. The materials used in dental treatment are one of these factors. We aimed to compare the results of dental series patch test in LP patients with and without oral involvement to determine whether the dental restorative materials play a role in the etiology of LP and to detect the effect of dental materials in cases where there is no oral involvement. Materials and Methods: The study involved a total of 38 patients who were admitted to the Dermatology Department and Dentistry Faculty Oral and Maxillofacial Surgery Department and were diagnosed with LP clinically and/or histopathologically. Nineteen of patients had oral involvement and the other 19 patients had no oral involvement. All of the patients received dental serial patch test. Results: Fourteen of the 19 patients with oral involvement (73.7%) and 15 patients without oral involvement (78.9%) showed positive reaction against at least one material. There was no statistically significant difference between the groups in terms of patch test positivity (p= 1.00). The allergens that mostly caused positive reaction against patch test in the group with oral involvement were copper sulfate and cobalt (II) cloride hexahydrate (23.3%). In the group without oral involvement the most common allergen that caused positive reaction was copper sulfate (% 47.3). Conclusion: The similarity of the allergens that caused positive reaction and the rate of positivity in dental serial patch test in the groups with and without oral involvement promote that the dental restorative materials may trigger the disease even in cases without oral LP. This study is a preliminary study due to the lack of a healthy control group and the small number of subjects.
Açıklama
Anahtar Kelimeler
Lichen planus, oral involvement, dental series patch test
Kaynak
Turkderm-Turkish Archives of Dermatology and Venerology
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
49
