Lupus psikozu tedavisinde intravenöz immünoglobulinlerin kullanımı: olgu sunumu
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Dosyalar
Tarih
1998
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turgut Özal Tıp Merkezi Dergisi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Sistemik lupus eritematosus (SLE) otoimmun bir mu/tisistem hastalığıdır. Belirtileri çok yönlüdür ve hemen her organı tutabilir. SLE genellikle çocuklarda erişkinlerden daha akut başlar ve ağır seyreder.
Son zamanlarda serebral lupuslu hastalarda intravenöz immunglobülinlerh oldukça iyi sonuçlar verdiği bildirilmektedir. Bu makalede, psikoz ve birden fazla organ tutulumu olan; yüksek doz intravenöz kortikosteroide yani vermeyen, IVIG uygulamasını takiben (400 mg/kg/gün, 5 gün/ay) psikoz tablosu tamamen düzelen bir SLE olgusu sunuldu.
Bu bulgu, IVIG'in SLE'nin konvansiyonel tedavisine yamt vemeyen olgularda, özellikle de serebral lupus da başarılı bir şekilde kullanılabileceğin desteklemektedir.
Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease. Its manifestations are protean and virtually any organ system can be involved. The disease in children is generally more acute and more severe than that in adult. Recently it has been notified that intravenous immunoglobulins (IVIG) in patients with cerebral lupus have improved fairly. In this report, we present a case of systemic lupus erythematosus involving multiple organ systems, including psychosis which did not respond to high-dose intravenous corticosteroid therapy. After application of IVIG (400 mg/kg/24 hr, 5 day/month) as an adjunctive agent, psychosis of the patient was completely improved. This report supports the finding that IVIG therapy may successfully be used for nonresponders to conventional treatments of SLE, especially for those with cerebral complications.
Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease. Its manifestations are protean and virtually any organ system can be involved. The disease in children is generally more acute and more severe than that in adult. Recently it has been notified that intravenous immunoglobulins (IVIG) in patients with cerebral lupus have improved fairly. In this report, we present a case of systemic lupus erythematosus involving multiple organ systems, including psychosis which did not respond to high-dose intravenous corticosteroid therapy. After application of IVIG (400 mg/kg/24 hr, 5 day/month) as an adjunctive agent, psychosis of the patient was completely improved. This report supports the finding that IVIG therapy may successfully be used for nonresponders to conventional treatments of SLE, especially for those with cerebral complications.
Açıklama
Turgut Özal Tıp Merkezi Dergisi, 5 (4).
Anahtar Kelimeler
Sistemik lupus eritematosus, intravenöz immunglobülin, çocuk, Systemic Lupus Erythematosus, immunoglobulins, child
Kaynak
Turgut Özal Tıp Merkezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
5
Sayı
4
Künye
Kabakuş, N.,Kuloğlu, M.,Yılmaz, E.,Aydınoğlu, H.,Atmaca, M., Aygün, A. D.,(1998). Lupus psikozu tedavisinde intravenöz immünoglobulinlerin kullanımı: olgu sunumu, 5 (4) 279-280.
