Uric Acid Level and Its Association with Carotid Intima-Media Thickness in Patients with Cardiac Syndrome X

dc.authoridPekdemir, Hasan/0000-0002-4913-5120
dc.authoridCansel, Mehmet/0000-0003-4740-4371
dc.authoridAkaycan, Jülide/0000-0002-9174-6777
dc.authorwosidErmis, Necip/HJP-7061-2023
dc.authorwosidPekdemir, Hasan/ABI-6096-2020
dc.authorwosidErmis, Necip/A-5184-2018
dc.authorwosidCansel, Mehmet/ABI-6324-2020
dc.authorwosidAkaycan, Jülide/ABI-2397-2020
dc.contributor.authorAcikgoz, Nusret
dc.contributor.authorErmis, Necip
dc.contributor.authorYagmur, Julide
dc.contributor.authorMuezzinoglu, Kubra
dc.contributor.authorKarakus, Yasin
dc.contributor.authorCansel, Mehmet
dc.contributor.authorPekdemir, Hasan
dc.date.accessioned2024-08-04T20:35:45Z
dc.date.available2024-08-04T20:35:45Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of our study was to evaluate serum uric acid level and its relationship with carotid intima-media thickness (CIMT) in patients with cardiac syndrome X (CSX). Subjects and Methods: A total of 50 patients with CSX (28 females/22 males, 51.0 +/- 10.9 years) and 40 controls (27 females/13 males, 53.0 +/- 10.2 years) were included in the study. All subjects underwent a noninvasive stress test and conventional coronary angiography. Serum uric acid levels were measured and B mode ultrasonography was performed to assess CIMT in all subjects. Results: Serum uric acid levels were higher in patients with CSX than in the control subjects (5.1 +/- 1.8 vs. 3.9 +/- 1.3 mg/dl; p = 0.002). The CIMT was higher in patients with CSX than in the control subjects (0.75 +/- 0.18 vs. 0.63 +/- 0.09 mm; p < 0.001). A significant correlation was found between serum uric acid values and CIMT measurements in patients with CSX (r = 0.666, p < 0.001). Conclusions: Serum uric acid levels were higher in patients with CSX and elevated serum uric acid levels were associated with carotid atherosclerosis, thereby indicating that elevated serum uric acid levels might contribute to the development of subclinical atherosclerosis in CSX patients. Copyright (C) 2011 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000332583
dc.identifier.endpage119en_US
dc.identifier.issn1011-7571
dc.identifier.issn1423-0151
dc.identifier.issue2en_US
dc.identifier.pmid22076385en_US
dc.identifier.scopus2-s2.0-84857364195en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage115en_US
dc.identifier.urihttps://doi.org/10.1159/000332583
dc.identifier.urihttps://hdl.handle.net/11616/95575
dc.identifier.volume21en_US
dc.identifier.wosWOS:000300616900003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectUric aciden_US
dc.subjectCarotid intima-media thicknessen_US
dc.subjectCardiac syndrome Xen_US
dc.titleUric Acid Level and Its Association with Carotid Intima-Media Thickness in Patients with Cardiac Syndrome Xen_US
dc.typeArticleen_US

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