A New Diagnostic Scoring for Discrimination of Tuberculous and Bacterial Meningitis on the Basis of Clinical and Laboratory Findings

Basit Öğe Kaydı
dc.authoridErsoy, Yuksel/0000-0002-8035-4532
dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authoridErsoy, Yasemin/0000-0001-5730-6682
dc.authoridmemişoğlu, funda/0000-0003-3905-1182
dc.authorwosidErsoy, Yuksel/S-7503-2016
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.authorwosidErsoy, Yasemin/AAE-4811-2020
dc.authorwosidmemişoğlu, funda/AAA-4392-2021
dc.contributor.authorErsoy, Yasemin
dc.contributor.authorYetkin, Funda
dc.contributor.authorBayraktar, Mehmet Refik
dc.contributor.authorErsoy, Yuksel
dc.contributor.authorYologlu, Saim
dc.date.accessioned2024-08-04T20:35:51Z
dc.date.available2024-08-04T20:35:51Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: The aim of this study was to develop a new diagnostic index (DI) on the basis of clinical and laboratory findings including serum C-reactive protein (CRP) for tuberculous meningitis (TM) and bacterial meningitis (BM). Subjects and Methods: During a 7-year period, 96 adult patients with meningitis (30 with TM and 66 with BM) were studied retrospectively. Multivariate logistic regression analysis was performed to investigate the diagnostic value of clinical and laboratory parameters as independent predictors on discrimination of tuberculous from BM patients. Results: Six features predictive for diagnosis including age, CSF leukocyte count, PML dominance, length of illness, serum CRP level and blood WBC count were used. The DI model developed from these features had very high sensitivity and specificity rates of 100.0 and 95.4%, respectively. The sensitivity and specificity rates were 97.4 and 100%, respectively, in microbiologically proven cases. Conclusion: Our results suggested that this new DI which consists of simple clinical and laboratory parameters had the power to discriminate adult patients with documented tuberculous and BM (excluding Brucella meningitis). It should, however, be tested in prospective studies. Copyright (C) 2011 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000333808
dc.identifier.endpage263en_US
dc.identifier.issn1011-7571
dc.identifier.issue3en_US
dc.identifier.pmid22133866en_US
dc.identifier.scopus2-s2.0-84859593156en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage259en_US
dc.identifier.urihttps://doi.org/10.1159/000333808
dc.identifier.urihttps://hdl.handle.net/11616/95617
dc.identifier.volume21en_US
dc.identifier.wosWOS:000305799100012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBacterial meningitisen_US
dc.subjectC-reactive proteinen_US
dc.subjectDiagnosticsen_US
dc.subjectTuberculosisen_US
dc.titleA New Diagnostic Scoring for Discrimination of Tuberculous and Bacterial Meningitis on the Basis of Clinical and Laboratory Findingsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu