Benzimidazolium-based novel silver N-heterocyclic carbene complexes: synthesis, characterisation and in vitro antimicrobial activity

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dc.authoridGünal, Selami/0000-0002-4752-5176
dc.authoridAkkoc, Senem/0000-0002-1260-9425
dc.authoridKayser, Veysel/0000-0003-1310-9534
dc.authoridSifniotis, Vicki/0000-0003-3750-9962
dc.authorwosidGök, Yetkin/AAA-5669-2021
dc.authorwosidAkkoç, Senem/AAN-1478-2021
dc.authorwosidÖzdemir, İlknur/AAA-6216-2021
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.authorwosidKayser, Veysel/HKN-5249-2023
dc.contributor.authorSari, Yakup
dc.contributor.authorAkkoc, Senem
dc.contributor.authorGok, Yetkin
dc.contributor.authorSifniotis, Vicki
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorGunal, Selami
dc.contributor.authorKayser, Veysel
dc.date.accessioned2024-08-04T20:41:36Z
dc.date.available2024-08-04T20:41:36Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study reports the synthesis, characterisation and antimicrobial activity of five novel silver N-heterocyclic carbene (Ag-NHC) complexes obtained by N-propylphthalimide and N-methyldioxane substituted benzimidazolium salts with silver oxide. The reactions were performed at room temperature for 24 h in the absence of light. The obtained complexes were identified and characterised by H-1 and C-13 NMR, FT-IR and elemental analysis techniques. The minimum inhibitory concentration (MIC) of the complexes was determined for E. coli, P. aeruginosa, E. faecalis, S. aureus, C. tropicalis and C. albicans in vitro through agar and broth dilution. The results indicated that these complexes exhibit antimicrobial activity. In particular, complex 3 presented the significant broad spectrum antimicrobial activity.en_US
dc.description.sponsorshipInonu University Research Fund [BAP 2011/25]en_US
dc.description.sponsorshipWe would like to thank the Inonu University Research Fund (BAP 2011/25) for financial support.en_US
dc.identifier.doi10.3109/14756366.2016.1156102
dc.identifier.endpage1530en_US
dc.identifier.issn1475-6366
dc.identifier.issn1475-6374
dc.identifier.issue6en_US
dc.identifier.pmid26987046en_US
dc.identifier.scopus2-s2.0-84961198097en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1527en_US
dc.identifier.urihttps://doi.org/10.3109/14756366.2016.1156102
dc.identifier.urihttps://hdl.handle.net/11616/97226
dc.identifier.volume31en_US
dc.identifier.wosWOS:000385270300086en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Enzyme Inhibition and Medicinal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial activityen_US
dc.subjectbenzimidazoleen_US
dc.subjectN-heterocyclic carbeneen_US
dc.subjectsilver complexen_US
dc.titleBenzimidazolium-based novel silver N-heterocyclic carbene complexes: synthesis, characterisation and in vitro antimicrobial activityen_US
dc.typeArticleen_US

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