Prognostic Value of Routine Biochemistry Profile of Liver Transplant Patients Admitted to the Emergency Department with a Suspected Infection

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dc.authoridKose, Adem/0000-0002-1853-1243
dc.authoridGur, Ali/0000-0002-7823-0266
dc.authorwosidGür, Ali/S-7601-2017
dc.authorwosidKose, Adem/AAD-1226-2020
dc.contributor.authorGur, Ali
dc.contributor.authorKose, Adem
dc.contributor.authorOguzturk, Hakan
dc.date.accessioned2024-08-04T20:50:38Z
dc.date.available2024-08-04T20:50:38Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Since patients who have undergone liver transplantation should take immunosuppressants for life, the prevalence of systemic infections after this procedure is very high. These infections are associated with increased mortality and morbidity. Objective: This study aimed to investigate the prognostic value of routine biochemistry profile and its relationship with mortality in liver transplant patients admitted to the emergency department (ED) with a suspected infection. Methods: Patients who had undergone liver transplantation were included in the study. The patients were divided into three groups of culture-negative, culture-positive and control. White blood cell (WBC) count, hemoglobin (Hb), platelet (Plt), international normalized ratio (INR), creatinine (Cr), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values as well as vital sign findings were comparatively evaluated in terms of their ability to show the presence of any infection and their correlation with mortality. Results: Totally, 142 patients were enrolled and were divided into the following three groups: 41 cases in culture-negative group, 30 cases in culture-positive group, and 71 cases in control group. There was not any significant difference between study groups in terms of age and sex ratio (p>0.05). The Hb and Plt values of the culture-positive patients were significantly lower, and their INR was significantly higher compared to those in control group (p<0.05). Fever, Hb, Plt, INR, AST and ALT values were factors that had a significant correlation with mortality in patients with an infection whethere culture-positive or culture-negative ones (p<0.05). Conclusions: In patients admitted to the ED with a history of liver transplantation, we recommend the evaluation of vital signs and Hb, PLt, and INR values to determine whether there is an infection or not. We can also state that mortality risk is higher in cases with low Hb and Plt levels and high INR, ALT, and AST values.en_US
dc.identifier.doi10.22114/ajem.v0i0.516
dc.identifier.issn2717-3593
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85114335622en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.22114/ajem.v0i0.516
dc.identifier.urihttps://hdl.handle.net/11616/100186
dc.identifier.volume5en_US
dc.identifier.wosWOS:000607736900010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTehran Univ Medical Sciencesen_US
dc.relation.ispartofFrontiers in Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEmergency Departmenten_US
dc.subjectInfectionsen_US
dc.subjectLiver Function Testsen_US
dc.subjectLiver Transplantationen_US
dc.subjectMortalityen_US
dc.titlePrognostic Value of Routine Biochemistry Profile of Liver Transplant Patients Admitted to the Emergency Department with a Suspected Infectionen_US
dc.typeArticleen_US

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