Investigation of monocyte HDL ratio as an indicator of inflammation and complete blood count parameters in patients with acne vulgaris

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dc.authoridTürkmen, Dursun/0000-0001-9076-4669
dc.authoridAltunisik, Nihal/0000-0001-6844-1097;
dc.authorwosidTürkmen, Dursun/ABG-3801-2020
dc.authorwosidAltunisik, Nihal/ABG-8567-2020
dc.authorwosidSener, Serpil/ABI-6229-2020
dc.contributor.authorTurkmen, Dursun
dc.contributor.authorAltunisik, Nihal
dc.contributor.authorSener, Serpil
dc.date.accessioned2024-08-04T20:48:46Z
dc.date.available2024-08-04T20:48:46Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAims Acne vulgaris is a common inflammatory skin disease that affects the pilosebaceous unit. Increased sebum production, hyperkeratosis in follicular infundibulum, inflammation andPropionibacterium acnesare among aetiological factors. Complete blood count (CBC) parameters are used as diagnosis biomarkers for many diseases related with inflammatory processes. Although monocyte/HDL ratio (MHR) has been defined as an inflammatory marker recently, we did not come across any studies about MHR in acne, which is known to be an inflammatory disease. The present study was conducted to compare CBC parameters and MHR levels in acne vulgaris patients and healthy controls (HCs). Methods Sixty-five acne vulgaris patients followed in our clinic between January 2018 and December 2019 and 36 HCs matching in terms of age and sex were included in the study. Patients and HCs were compared in terms of CBC parameters [neutrophil, monocyte, platelet, lymphocyte, neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), platelet/lymphocyte (PLR)], HDL and MHR ratio. Results When compared with the HCs, acne vulgaris patients had statistically significantly higher neutrophil, NLR ratio and HDL (P = .042,P = .011 andP = .014, respectively). No statistically significant difference was found between acne vulgaris patients and the HCs in terms of other CBC parameters and MHR ratio (P > .05). Conclusions We believe that prospective studies consisting of large patient series are needed to understand whether CBC parameters and MHR ratio can be used as an inflammatory marker in acne vulgaris patients.en_US
dc.identifier.doi10.1111/ijcp.13639
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue12en_US
dc.identifier.pmid32741037en_US
dc.identifier.scopus2-s2.0-85089253853en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.13639
dc.identifier.urihttps://hdl.handle.net/11616/99450
dc.identifier.volume74en_US
dc.identifier.wosWOS:000558052900001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHigh-Density-Lipoproteinen_US
dc.subjectCholesterol Ratioen_US
dc.subjectLymphocyte Ratioen_US
dc.subjectNeutrophilen_US
dc.subjectPsoriasisen_US
dc.subjectPlateleten_US
dc.titleInvestigation of monocyte HDL ratio as an indicator of inflammation and complete blood count parameters in patients with acne vulgarisen_US
dc.typeArticleen_US

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