Comparison between radiological and invasive diagnostic modalities in diagnosis of breast cancer

dc.authorscopusid56676161700
dc.authorscopusid6508044054
dc.authorscopusid55625085700
dc.authorscopusid58512765900
dc.authorscopusid8085605300
dc.authorscopusid15727049000
dc.authorscopusid12787163300
dc.contributor.authorOnur G.O.
dc.contributor.authorTarcan E.
dc.contributor.authorOnur A.
dc.contributor.authorCan H.
dc.contributor.authorAtahan M.K.
dc.contributor.authorYigit S.C.
dc.contributor.authorCakalagaoglu F.
dc.date.accessioned2024-08-04T20:02:26Z
dc.date.available2024-08-04T20:02:26Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Breast cancer is the most common cause of deaths of cancer in women. Nowadays, following completion of imaging methods, mainly fine needle aspiration biopsy (FNAB) and core biopsy methods have been used for establishing cytopathological diagnosis although discussions regarding superiority continue. Materials and Methods: Those with a complaint of "mass in breast" along with those diagnosed to have a mass as a result of routine physical examination among all patients applying to our clinic between 01.01.2009 and 31.12.2011 were retrospectively assessed. Totals of 146 and 64 patients with complete radiological observation who had undergone FNAB and core biopsies, respectively, were evaluated. Postoperative pathological results of patients of both groups receiving surgery were also taken into consideration. All results were compared in terms of false positivity/negativity, sensitivity/specifity, surgery types and distribution of postoperative results with regard to diagnoses along with those of malignant/benign masses with regard to quadrants determined. Results: Diagnostic malignancy power of mammographic BIRADS classification was 87.3%. However, the value was 75% in the core biopsy group. Sensitivity and specifity following comparison of FNAB and postoperative pathology results of those receiving surgery were 85.4% and 92.9% while they were 93.5% and 100% in the core biopsy group. Diagnostic malignancy power, calculated by determining AUC in ROC analysis, of FNAB was 89.1% while that of core biopsy was 96.7%. Conclusions: It was shown that core biopsy is superior to FNAB in terms of sensitivity, specificity and accurate histopathological classification. However; quick, cheap and basic diagnosis by means of FNAB should not be ignored. Sensitivity of FNAB is rather high in experienced hands and furthermore it would be expected to be lower than with core biopsy.en_US
dc.identifier.doi10.7314/APJCP.2015.16.10.4323
dc.identifier.endpage4328en_US
dc.identifier.issn1513-7368
dc.identifier.issue10en_US
dc.identifier.pmid26028093en_US
dc.identifier.scopus2-s2.0-84930707242en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage4323en_US
dc.identifier.urihttps://doi.org/10.7314/APJCP.2015.16.10.4323
dc.identifier.urihttps://hdl.handle.net/11616/91692
dc.identifier.volume16en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAsian Pacific Organization for Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast canceren_US
dc.subjectComparisonen_US
dc.subjectCore biopsyen_US
dc.subjectFNABen_US
dc.subjectSensitivityen_US
dc.subjectSpecificityen_US
dc.titleComparison between radiological and invasive diagnostic modalities in diagnosis of breast canceren_US
dc.typeArticleen_US

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