Continuous Ambulatory Peritoneal Dialysis-Related Peritonitis: Clinical Characteristics, Etiological Agents and Their Antibiotic Susceptibilities

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dc.authoridOzden, Mehmet/0000-0002-1202-0864
dc.authorwosidDemirdag, Kutbeddin/W-6168-2018
dc.authorwosidTARTAR, Ayşe SAĞMAK/W-6397-2018
dc.authorwosidOzden, Mehmet/ABI-5449-2020
dc.contributor.authorSagmak-Tartar, Ayse
dc.contributor.authorOzden, Mehmet
dc.contributor.authorAkbulut, Ayhan
dc.contributor.authorDemirdag, Kudbettin
dc.contributor.authorOzer-Balin, Safak
dc.date.accessioned2024-08-04T20:42:53Z
dc.date.available2024-08-04T20:42:53Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The objective of this study was to determine clinical characteristics, etiological agents, and their antibiotic susceptibilities in continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis encountered in our hospital. Methods: Thirty patients with peritonitis attack among 55 adult patients aged >= 18 years, who applied to Nephrology Clinic of Firat University Hospital between January 2012 and February 2013 and who were monitored in the CAPD unit were included in this prospective study. Cultures were performed on both solid media and blood culture bottles according to the recommendations of International Society for Peritoneal Dialysis. Antibiotic susceptibilities were investigated by disk diffusion method. Results: During clinical evaluation, abdominal guarding (n=28, 93.3%), rebound tenderness (n=4, 13.3%), fever (n=9, 30%), nausea and vomiting (n=13, 43.3%), and diarrhea (n=5, 16.7%) were detected. Turbid dialysis fluid and abdominal pain were noted in all patients. Direct Gram staining yielded positive result in 1 (3.3%) patient. In 28 (93.3%) patients bacterial growth was detected in the cultures. Bacterial growth was detected on solid culture media in 14 (46.7%), and blood culture bottles in 28 (93.3%) patients. In 2 (6.7%) patients, bacterial growth was not detected in both media. The same microorganisms were identified in both methods, and their antibiograms yielded similar results. Gram-positives included coagulase-negative staphylococci (n=16, 57.1%), Staphylococcus aureus (n=4, 14.3%), streptococci (n=4, 14.3%), and enterococci (n=1, 3.6%). Gram-negatives consisted of Escherichia coli (n=2), and Yersinia enterocolitica (n=1). In 46.2% of Gram-positive microorganisms penicillin resistance was detected, while 9.5% of staphylococci were methicillin-resistant. Conclusions: Each health center should have knowledge of its prevalent microbial agents, and their susceptibility profile, which is essential for the determination of suitable alternative empirical treatment. This strategy will obviate unnecessary use of antibiotics, and contribute to the decrease in the potential development of antibiotic resistance.en_US
dc.identifier.doi10.5152/kd.2016.26
dc.identifier.endpage111en_US
dc.identifier.issn1301-143X
dc.identifier.issn1309-1484
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85008230359en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage107en_US
dc.identifier.urihttps://doi.org/10.5152/kd.2016.26
dc.identifier.urihttps://hdl.handle.net/11616/97651
dc.identifier.volume29en_US
dc.identifier.wosWOS:000390774000003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherAvesen_US
dc.relation.ispartofKlimik Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectContinuous ambulatory peritoneal dialysisen_US
dc.subjectperitonitisen_US
dc.subjectanti-bacterial agentsen_US
dc.titleContinuous Ambulatory Peritoneal Dialysis-Related Peritonitis: Clinical Characteristics, Etiological Agents and Their Antibiotic Susceptibilitiesen_US
dc.typeArticleen_US

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