N-heterocyclic carbene based ruthenium complexes for selective ?-C(sp3)-H functionalization of N-fused saturated cyclic amines
| dc.contributor.author | Kaloglu, Nazan | |
| dc.date.accessioned | 2024-08-04T20:45:50Z | |
| dc.date.available | 2024-08-04T20:45:50Z | |
| dc.date.issued | 2019 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Herein, a series of new ruthenium(II) complexes with the general molecular formula [RuCl2(arene)(NHC)], (arene = eta(6)-p-cymene, NHC = N-heterocyclic carbene) were synthesized from in situ prepared silver(I)-NHCs by the transmetallation method. These complexes were fully characterized by analytical and spectral methods. Ruthenium(11) complexes were tested as promising catalyst for selective B-C(sp(3))-H functionalization of N-methylpiperidine with various aldehydes through hydrogen transfers in presence of external acidic additive. These eco-friendly cross-dehydrogenative couplings enable the production of C(3)-alkylated N-methylpiperidine derivatives without enamines with only carbon dioxide and water as benign by-product. (C) 2019 Elsevier Ltd. All rights reserved. | en_US |
| dc.identifier.doi | 10.1016/j.tet.2018.12.049 | |
| dc.identifier.endpage | 2272 | en_US |
| dc.identifier.issn | 0040-4020 | |
| dc.identifier.issue | 15 | en_US |
| dc.identifier.scopus | 2-s2.0-85062606523 | en_US |
| dc.identifier.scopusquality | Q2 | en_US |
| dc.identifier.startpage | 2265 | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.tet.2018.12.049 | |
| dc.identifier.uri | https://hdl.handle.net/11616/98712 | |
| dc.identifier.volume | 75 | en_US |
| dc.identifier.wos | WOS:000463288100003 | en_US |
| dc.identifier.wosquality | Q2 | en_US |
| dc.indekslendigikaynak | Web of Science | en_US |
| dc.indekslendigikaynak | Scopus | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Pergamon-Elsevier Science Ltd | en_US |
| dc.relation.ispartof | Tetrahedron | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | N-Heterocyclic carbene | en_US |
| dc.subject | Ruthenium | en_US |
| dc.subject | Cyclic amine | en_US |
| dc.subject | Catalysis | en_US |
| dc.subject | beta-alkylation | en_US |
| dc.title | N-heterocyclic carbene based ruthenium complexes for selective ?-C(sp3)-H functionalization of N-fused saturated cyclic amines | en_US |
| dc.type | Article | en_US |
