Dust-mites: Effect on lipid peroxidation

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dc.authoridbay karabulut, aysun/0000-0002-7873-2805
dc.authorwosidbay karabulut, aysun/HJP-0995-2023
dc.contributor.authorAtambay, Metin
dc.contributor.authorKarabulut, Aysun Bay
dc.contributor.authorAycan, Ozlem Makbule
dc.contributor.authorKilic, Eser
dc.contributor.authorYazar, Suleyman
dc.contributor.authorSaraymen, Recep
dc.contributor.authorKaraman, Ulku
dc.date.accessioned2024-08-04T20:15:26Z
dc.date.available2024-08-04T20:15:26Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. Dust-mites are present in our homes, feed on dead exfoliated skin and other organic material. It is also known that oxidative stress may lead to cellular damage that can be confirmed by markers of cellular disruption. Oxidative stress in various infective processes has been documented. We investigated whether house dust-mites cause oxidative stress in patients. Methods. Products of lipid peroxidation in erythrocytes and lymphocytes were assessed by measuring malondialdehyde concentration. Results, Our results showed that patients who had a positive skin test for dust-mite antigens and had dust-mites present in their houses (dust-mite positive) had increased erythrocyte malondialdehyde levels (62.39 [18.56]. nmol/g-Hb) compared with those who were skin test positive, dust-mite negative (45.45 [10.82]) or skin test negative, dust-mite negative (42.20 [5.68]). They also had significantly higher levels of lymphocyte malondialdehyde (4.22 [0.55] nmol/g-protein), compared with those who were skin test positive, dust-mite negative (3.46 [0.29]) or skin test negative, dust-mite negative (1.25 [0.31]; p < 0.05). However, there was no statistically significant difference between the malondialdehyde levels of dust-mite negative/skin test positive and dust-mite negative/skin test negative patients. Conclusion. Increased malondialdehyde activity in lymphocytes and erythrocytes in the dust-mite positive/skin test positive group shows the presence of the oxidative stress in patients with dust-mite infestation.en_US
dc.identifier.endpage77en_US
dc.identifier.issn0970-258X
dc.identifier.issue2en_US
dc.identifier.pmid16756194en_US
dc.identifier.scopus2-s2.0-33646831818en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage75en_US
dc.identifier.urihttps://hdl.handle.net/11616/94389
dc.identifier.volume19en_US
dc.identifier.wosWOS:000237842900007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAll India Inst Medical Sciencesen_US
dc.relation.ispartofNational Medical Journal of Indiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHuman-Erythrocytesen_US
dc.subjectMalondialdehydeen_US
dc.titleDust-mites: Effect on lipid peroxidationen_US
dc.typeArticleen_US

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