Impact of telephonic interviews on persistence and daily adherence to insulin treatment in insulin-naive type 2 diabetes patients: dropout study

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dc.authoridSahin, Ibrahim/0000-0002-6231-0034
dc.authoridOguz, Aytekin/0000-0002-2595-5167
dc.authoridGogas Yavuz, Dilek/0000-0002-0075-6313
dc.authorwosidŞahin, İbrahim/HHY-8303-2022
dc.authorwosidSert, Murat/G-6103-2018
dc.authorwosidSahin, Ibrahim/ABI-6050-2020
dc.authorwosidOguz, Aytekin/AAJ-2732-2021
dc.authorwosidGogas Yavuz, Dilek/GRR-7277-2022
dc.contributor.authorYavuz, Dilek Gogas
dc.contributor.authorBilen, Habip
dc.contributor.authorSancak, Seda
dc.contributor.authorGarip, Tayfun
dc.contributor.authorHekimsoy, Zeliha
dc.contributor.authorSahin, Ibrahim
dc.contributor.authorYilmaz, Murat
dc.date.accessioned2024-08-04T20:41:46Z
dc.date.available2024-08-04T20:41:46Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The objective of this study is to evaluate the impact of sequential telephonic interviews on treatment persistence and daily adherence to insulin injections among insulin-naive type 2 diabetes patients initiated on different insulin regimens in a 3-month period. Methods: A total of 1,456 insulin-naive patients with type 2 diabetes (mean [standard deviation, SD] age: 56.0 [12.0] years, 49.1% were females) initiated on insulin therapy and consecutively randomized to sequential (n=733) and single (n=723) telephonic interview groups were included. Data on insulin treatment and self-reported blood glucose values were obtained via telephone interview. Logistic regression analysis was performed for factors predicting increased likelihood of persistence and skipping an injection. Results: Overall, 76.8% patients (83.2% in sequential vs 70.3% in single interview group, (P<0.001) remained on insulin treatment at the third month. Significantly higher rate for skipping doses was noted in basal bolus than in other regimens (27.0% vs 15.0% for premixed and 15.8% basal insulin, respectively, P<0.0001). Logistic regression analysis revealed sequential telephonic interview (odds ratio [OR], 1.531; 95% confidence interval [CI], 1.093-2.143; P=0.013), higher hemoglobin A1c levels (OR, 1.090; 95% CI, 0.999-1.189; P=0.049), and less negative appraisal of insulin therapy as significant predictors of higher persistence. Basal bolus regimen (OR, 1.583; 95% CI, 1.011-2.479; P=0.045) and higher hemoglobin A1c levels (OR, 1.114; 95% CI, 1.028-1.207; P=0.008) were the significant predictors of increased likelihood of skipping an injection. Conclusion: Our findings revealed positive influence of sequential telephonic interview, although including no intervention in treatment, on achieving better treatment persistence in type 2 diabetes patients initiating insulin.en_US
dc.identifier.doi10.2147/PPA.S100626
dc.identifier.endpage861en_US
dc.identifier.issn1177-889X
dc.identifier.pmid27274207en_US
dc.identifier.scopus2-s2.0-84969791996en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage851en_US
dc.identifier.urihttps://doi.org/10.2147/PPA.S100626
dc.identifier.urihttps://hdl.handle.net/11616/97337
dc.identifier.volume10en_US
dc.identifier.wosWOS:000376272200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDove Medical Press Ltden_US
dc.relation.ispartofPatient Preference and Adherenceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecttype 2 diabetesen_US
dc.subjectinsulin analogsen_US
dc.subjectHbA1cen_US
dc.subjectself-monitoring of blood glucoseen_US
dc.titleImpact of telephonic interviews on persistence and daily adherence to insulin treatment in insulin-naive type 2 diabetes patients: dropout studyen_US
dc.typeArticleen_US

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