The effect of prone position on oxygen saturation, blood gas parameters, and respiratory rate in intensive care patients with COVID-19-induced ARDS

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dc.contributor.authorTekin, Veysel
dc.contributor.authorKorkmaz, Medet
dc.date.accessioned2026-04-04T13:34:41Z
dc.date.available2026-04-04T13:34:41Z
dc.date.issued2025
dc.departmentİnönü Üniversitesi
dc.description.abstractThis study aimed to evaluate the short-term effect of prone positioning on oxygen saturation, arterial blood gas parameters, and respiratory rate in intensive care patients with COVID-19-induced acute respiratory distress syndrome (ARDS). This randomized experimental study used a six-measure time series design with control and intervention groups. A total of 90 intubated patients diagnosed with COVID-19 and ARDS were enrolled, with 45 patients in the experimental group and 45 in the control group. The experimental group received a 30-minute prone positioning session, while no intervention was applied to the control group. Data were collected using a Demographic Information Form and a structured form to record oxygen saturation, blood gas parameters, and respiratory rate. This study was registered at ClinicalTrials.gov (Identifier: NCT06997666; first posted on 28/05/2025). Age and gender were comparable between groups (p > 0.05). Patients in the experimental group demonstrated higher mean values of peripheral oxygen saturation (SpO(2)), arterial oxygen saturation (SaO(2)), and partial pressure of oxygen (PaO2), along with lower PaCO2 and respiratory rates. No significant changes were observed in sodium or lactate levels. All effects observed were immediate and short-term. No adverse events or unintended effects were reported. A single short-duration session of prone positioning resulted in immediate physiological improvements in oxygenation, ventilation parameters, and respiratory rate in patients with COVID-19-related ARDS. Further studies are needed to assess long-term clinical outcomes and sustained benefits.
dc.identifier.doi10.1038/s41598-025-28844-3
dc.identifier.issn2045-2322
dc.identifier.issue1
dc.identifier.pmid41318642
dc.identifier.scopus2-s2.0-105026394560
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1038/s41598-025-28844-3
dc.identifier.urihttps://hdl.handle.net/11616/109332
dc.identifier.volume16
dc.identifier.wosWOS:001653310500004
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNature Portfolio
dc.relation.ispartofScientific Reports
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250329
dc.subjectARDS
dc.subjectCOVID-19
dc.subjectNursing
dc.subjectBlood gas values
dc.subjectProne position
dc.titleThe effect of prone position on oxygen saturation, blood gas parameters, and respiratory rate in intensive care patients with COVID-19-induced ARDS
dc.typeArticle

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