Histopathological subtyping of actinic keratosis and it's coexistence with nonmelanotic skin cancers in Gaziantep and Malatya regions
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Deri Zuhrevi Hastaliklar Dernegi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background and Design: Actinic (solar) keratosis (AK) is a precancerous, epidermal lesion, which develops in sensitive skin exposed to sun for a long period. AKs are divided into different histopathological subtypes. There is a link between the clinical progression of the histopathological subtypes, the degree of cellular atypia, and the precancerous nature of the lesion. Different series have reported that the rate of transformation of AK to squamous cell carcinoma (SCC) ranges between 12% and 20%. Materials and Methods: In this study, we reevaluated patients who were diagnosed with AK in the Pathology Departments of the Medical Faculties of Inonu and Gaziantep Universities over an eight-year period, and divided the patients into different histopathological subtypes. In addition, we investigated the association between the lesions, and basal cell carcinoma (BCC), SCC and both carcinomas. Results: 29,6% of cases were proliferative AK, 27% of cases were hypertrophic AK. 19% and 13% of all lesions was associated with BCC and SCC, respectively. Conclusion: In this study, we found that the most frequent subtype was proliferative AK and the most frequent nonmelanotic skin cancer was BCC associated with AK.
Açıklama
Anahtar Kelimeler
Actinic keratosis, solar keratosis, histopathology, non melanotic skin cancers
Kaynak
Turkderm-Turkish Archives of Dermatology and Venerology
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
50
Sayı
3
