Risk factors for epilepsy following arterial ischemic stroke childhood: A retrospective cohort study

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dc.authoridARSLAN, Ahmet Kadir/0000-0001-8626-9542
dc.authorwosidARSLAN, Ahmet Kadir/AAA-2409-2020
dc.contributor.authorYucel, Guel
dc.contributor.authorArslan, Ahmet Kadir
dc.contributor.authorOzgor, Bilge
dc.contributor.authorGungor, Serdal
dc.date.accessioned2024-08-04T20:56:08Z
dc.date.available2024-08-04T20:56:08Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: PSE is reported more frequently in childhood than in adults. In this study, we aimed to investigate potential risk factors for the development of post-stroke epilepsy (PSE) in children with arterial ischemic stroke (AIS). Material methods: The current retrospective cohort study included the medical records of 50 pediatric participants (aged 29 days to 18 years) diagnosed with AIS at a university hospital between January 2006 and December 2023. All information of the patients who were followed for at least two years for the development of PSE after AIS was entered into the hospital database and recorded in a pre-designed questionnaire. Acute symptomatic seizures were defined as seizures occurring within 7 days after stroke. Two or more late seizures occurring after the acute period (>7 days) were classified as PSE. The incidence of PSE and potential risk factors were investigated. Results: After AIS, more than half of the patients (58 %) developed acute seizures and almost one-third (38 %) developed PSE. Risk factors associated with the development of PSE, very early seizures (within the first six hours), high stroke severity, cortical lesions, neurological deficits and low serum vitamin D levels were detected (p = 0.05, p = 0.036, p = 0.011, p < 0.001, p < 0.001, respectively). Conclusion: Seizures within the first six hours, high stroke severity, and neurological deficits are important risk factors for the development of PSE in children. Knowing the potential risk factors of PSE may be helpful for clinicians to identify high-risk patients. It can also contribute to treatment decision-making and post-discharge follow-up planning.en_US
dc.identifier.doi10.1016/j.yebeh.2024.109873
dc.identifier.issn1525-5050
dc.identifier.issn1525-5069
dc.identifier.pmid38936215en_US
dc.identifier.scopus2-s2.0-85196790302en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.yebeh.2024.109873
dc.identifier.urihttps://hdl.handle.net/11616/102078
dc.identifier.volume157en_US
dc.identifier.wosWOS:001262316100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAcademic Press Inc Elsevier Scienceen_US
dc.relation.ispartofEpilepsy & Behavioren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArterial ischemic strokeen_US
dc.subjectSeizuresen_US
dc.subjectEpilepsyen_US
dc.subjectRisk factorsen_US
dc.subjectChildhooden_US
dc.subjectPediatricen_US
dc.titleRisk factors for epilepsy following arterial ischemic stroke childhood: A retrospective cohort studyen_US
dc.typeArticleen_US

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