Dermatological signs in Wilson's disease

dc.contributor.authorSeyhan, Muammer
dc.contributor.authorErdem, Teoman
dc.contributor.authorSelimoglu, Mukadder A.
dc.contributor.authorErtekin, Vildan
dc.date.accessioned2024-08-04T20:31:15Z
dc.date.available2024-08-04T20:31:15Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBecause no data on skin and mucosal findings of patients with Wilson's disease have been published so far, the aim of the present study was to investigate the prevalence of mucosal and skin findings in childhood Wilson's disease and to determine its specific dermatological findings, if any exist. Thirty-seven 4-17-year-old children with Wilson's disease were included. A complete skin, scalp skin, mucous membrane and nail examination was performed. Of the children, 26 (70.3%) had at least one dermatological finding. Twenty-five (67.6%), five (13.5%), nine (24.3%) had at least one skin, mucosal and nail finding, respectively. The most prevalent dermatological diagnosis of the Wilson's disease patients was xerosis (45.7%). The presence of dermatological findings was not related to drug usage, severity of the disease, or malnutrition. The duration of the disease was not different in patients with or without dermatological findings. The frequency of skin findings alone, however, was high in relatively newly diagnosed patients (< 2 years). Dermatologist should be aware of the various dermatological manifestations of Wilson's disease, because a careful and objective skin, mucosa, nail and hair examination may be indicative of a diagnosis of Wilson's disease, particularly in early cases.en_US
dc.identifier.doi10.1111/j.1442-200X.2008.02766.x
dc.identifier.endpage398en_US
dc.identifier.issn1328-8067
dc.identifier.issn1442-200X
dc.identifier.issue3en_US
dc.identifier.pmid19400828en_US
dc.identifier.scopus2-s2.0-66549102154en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage395en_US
dc.identifier.urihttps://doi.org/10.1111/j.1442-200X.2008.02766.x
dc.identifier.urihttps://hdl.handle.net/11616/94807
dc.identifier.volume51en_US
dc.identifier.wosWOS:000266465700015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatrics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchildrenen_US
dc.subjectmucosaen_US
dc.subjectnailen_US
dc.subjectskinen_US
dc.subjectWilson's diseaseen_US
dc.titleDermatological signs in Wilson's diseaseen_US
dc.typeArticleen_US

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