Possible predictive clinical and radiological markers in decision making for surgical intervention in patients with Chiari Malformation type 1

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dc.authoridBAKAR, BULENT/0000-0002-6236-7647
dc.authoridAlhan, Aslihan/0000-0003-3945-9073
dc.authorwosidBurulday, Veysel/V-6075-2017
dc.contributor.authorYuksel, Ulas
dc.contributor.authorBurulday, Veysel
dc.contributor.authorAkkaya, Suleyman
dc.contributor.authorBaser, Selcuk
dc.contributor.authorOgden, Mustafa
dc.contributor.authorAlhan, Aslihan
dc.contributor.authorBakar, Bulent
dc.date.accessioned2024-08-04T20:52:05Z
dc.date.available2024-08-04T20:52:05Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground The first aim of this study was to compare the clinical data and posterior fossa morphometry obtained during the admission to the hospital between control group individuals (who had not Chiari Malformation (CM) type 1) and CM type 1 patients treated surgically or not. The second aim was to create a valid and reliable scale that can predict the decision-making for surgical intervention simply and easily in these patients. Materials Medical data and radiological images of 70 CM type 1 patients during their admission to the hospital were compared with the data of 69 control group individuals. Results Conservative treatment and/or follow-up was applied to 58 (82.9%) patients, and 12 (17.1%) patients underwent surgery. ROC analysis showed that the presence of myelopathy, tonsillar herniation >8 mm, Chamberlain line >84 mm, McRae line >44.50 mm, and odontoid process-McRae line angle <10.50 degrees could be used as predictive markers in decision-making for surgical intervention (p < 0.05). Logistic Regression analysis revealed that symptoms severity, and McRae line value would be the 'best parameters' in decision-making for surgical intervention (p < 0.05). A scale named the CHIASURG scale developed using this study's parameters showed that the parameters of 'depth of tonsillar herniation', 'Chamberlain line', and 'McRae line' could predict the surgical intervention risk. Conclusion It was found that symptoms severity and McRae line value could be used as predictive markers in decision-making for surgical intervention. Additionally, it was concluded that a new scale called CHIASURG could predict surgical intervention risk validly and reliably.en_US
dc.identifier.doi10.1080/01616412.2022.2089402
dc.identifier.endpage988en_US
dc.identifier.issn0161-6412
dc.identifier.issn1743-1328
dc.identifier.issue11en_US
dc.identifier.pmid35758154en_US
dc.identifier.scopus2-s2.0-85132855365en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage975en_US
dc.identifier.urihttps://doi.org/10.1080/01616412.2022.2089402
dc.identifier.urihttps://hdl.handle.net/11616/100746
dc.identifier.volume44en_US
dc.identifier.wosWOS:000815821500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofNeurological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChiari malformationen_US
dc.subjectsurgeryen_US
dc.subjectpredictive markeren_US
dc.subjectMcRae lineen_US
dc.titlePossible predictive clinical and radiological markers in decision making for surgical intervention in patients with Chiari Malformation type 1en_US
dc.typeArticleen_US

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