Comparison of analgesic effects of intravenous dexketoprofen trometamol, lornoxicam and paracetamol on postoperative pain after total abdominal hysterectomy

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dc.authorscopusid55898201200
dc.authorscopusid34569135700
dc.authorscopusid7005217039
dc.authorscopusid52464396900
dc.authorscopusid7801413617
dc.authorscopusid6604070029
dc.authorscopusid7004486274
dc.contributor.authorGülhaş N.
dc.contributor.authorDurmuş M.
dc.contributor.authorYücel A.
dc.contributor.authorŞahin T.
dc.contributor.authorErdil F.A.
dc.contributor.authorYolo?lu S.
dc.contributor.authorErsoy M.O.
dc.date.accessioned2024-08-04T20:02:06Z
dc.date.available2024-08-04T20:02:06Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: This study was intended to evaluate the analgesic efficacy of intravenously administered dexketoprofen trometamol in comparison with lornoxicam and paracetamol for acute postoperative pain. Material and Methods: 120 ASA physical status I-II patients undergoing total abdominal hysterectomy were enrolled in this study and randomly allocated into four groups (Groups D, L, P, and C). Following standard monitorization, in all groups, induction of anaesthesia was achieved via intravenous route using 5-7 mg kg-1 thiopental, 1 ?g kg-1 fentanyl, and 0.1 mg kg-1 vecuronium bromide, and also 6-8 % concentration of desflurane in 50 % O2 50 % N2O was used for the maintenance of anaesthesia in all groups. Patients received intravenous dexketoprofen trometamol 50 mg (Group D), 8 mg lornoxicam (Group L), 1 g paracetamol (Group P) and 100 mL SF (Group C) 30 min before the end of the surgery and 8-16 h after the surgery in Groups D, L, C. Group P received rescue medication at 6., 12., 18. and 24h after the surgery. At the end of the surgery, all patients received fentanyl via a patient controlled iv analgesia (PCA) device. Pain scores, cumulative fentanyl consumption, and patient satisfaction scores were assessed at 30 min, 2., 4., 6., 12. and 24h postoperatively. Results: The VAS scores at all evaluation time points, were similar among the groups. Fentanly consumption at 6., 12. and 24h postoperatively in Group P, L, and D was significantly lower when compared with Group C (p<0,05). Fentanyl consumption in Group L was lower relative to the other groups without any statistical significance. The patients' satisfaction scores at 6., 12. and 24h postoperatively in Group L were higher than the other groups (p<0,05). There was no significant difference between groups regarding sedation scores and side effects observed like postoperative nausea and vomiting and indigestion. Conclusion: We concluded that iv paracetamol, lornoxicam and dexketoprofen trometamol were equivalent in terms of analgesic efficiency in the management of postoperative pain after total abdominal hysterectomy.en_US
dc.identifier.doi10.5222/JTAICS.2011.176
dc.identifier.endpage181en_US
dc.identifier.issn1304-0871
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-80052920125en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage176en_US
dc.identifier.urihttps://doi.org/10.5222/JTAICS.2011.176
dc.identifier.urihttps://hdl.handle.net/11616/91429
dc.identifier.volume39en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntravenousen_US
dc.subjectLornoxicam and dexketoprofen trometamolen_US
dc.subjectParacetamolen_US
dc.subjectPostoperative painen_US
dc.titleComparison of analgesic effects of intravenous dexketoprofen trometamol, lornoxicam and paracetamol on postoperative pain after total abdominal hysterectomyen_US
dc.title.alternativeTotal Abdominal Histerektomilerde İntravenöz Deksketoprofen Trometamol, Lornoksikam ve Parasetamolün Etkinliklerinin Karşılaştırılmasıen_US
dc.typeArticleen_US

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