Differential Pulse Voltammetric (DPV) Determination of the Local Anesthetic Bupivacaine using Polyimide Membrane-Based Electrodes

Basit Öğe Kaydı
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridgüngör, öznur/0000-0002-0664-1218;
dc.authorwosidKöytepe, Süleyman/AAA-4168-2021
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidgüngör, öznur/ABG-9274-2020
dc.authorwosidErdogan, Mehmet Ali/ABI-7224-2020
dc.contributor.authorGungor, Oznur
dc.contributor.authorOzcan, Imren
dc.contributor.authorErdogan, Mehmet Ali
dc.contributor.authorAtes, Burhan
dc.contributor.authorKoytepe, Suleyman
dc.date.accessioned2024-08-04T20:47:03Z
dc.date.available2024-08-04T20:47:03Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAromatic selective polyimide (PI) membrane based voltammetric electrodes were prepared for bupivacaine measurements. Polyimide membranes were synthesized from 4,4 '-diaminobenzanilide (DABA) and different aromatic dianhydrides (pyromellitic dianhydride (PMDA), benzophenone-3,3 ',4,4 '-tetracarboxylic dianhydride (BPDA), 4,4 '-oxydiphthalic anhydride (ODPA)) through two-step polycondenzation reactions. The structural properties of the obtained benzanilide based PIs were characterized by various analytical techniques. For the preparation of voltammetric electrodes, these polyimide films were coated with polyimide solution by drop-casting on the surface of a platinum working electrode. Due to the excellent film properties and suitable porosity, the prepared benzanilide based polyimide films were used as the membrane for selective determination of bupivacaine in the presence of interferents that included lactose, glucose and sucrose. For this reason, the selectivity of the modified electrode to bupivacaine obtained from the prepared PI film toward the potential interferences was investigated by differential pulse voltammetry (DPV). The results of voltammetric study showed that polyimide films responded to only bupivacaine at a potential of approximately +0.92 V. The polyimide membrane modified electrode showed a rapid response time, a high R-value of 0.9941, high reproducibility and good selectivity for bupivacaine. The limit of detection (LOD) and the limit of quantitation (LOQ) were determined to be 16.82 mu M and 50.46 mu M, respectively. Thus, benzanilide based polyimides may be successfully used as selective membranes for preparation of bupivacaine sensors. This structure may be a precursor for the preparation of simultaneous or needle-shaped sensors in the future.en_US
dc.identifier.doi10.1080/00032719.2019.1646752
dc.identifier.endpage244en_US
dc.identifier.issn0003-2719
dc.identifier.issn1532-236X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85077477466en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage228en_US
dc.identifier.urihttps://doi.org/10.1080/00032719.2019.1646752
dc.identifier.urihttps://hdl.handle.net/11616/99132
dc.identifier.volume53en_US
dc.identifier.wosWOS:000479555400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofAnalytical Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject4en_US
dc.subject4 '-diaminobenzanilide (DABA)en_US
dc.subjectbupivacaineen_US
dc.subjectdifferential pulse voltammetry (DPV)en_US
dc.subjectoxydiphytalicanhydride (ODPA)en_US
dc.subjectpolyimide membraneen_US
dc.subjectvoltammetric sensoren_US
dc.titleDifferential Pulse Voltammetric (DPV) Determination of the Local Anesthetic Bupivacaine using Polyimide Membrane-Based Electrodesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu